IMIST


Gigaseal Formation in Patch Clamping (notice n° 43277)

000 -LEADER
fixed length control field 03174nam a22004935i 4500
001 - CONTROL NUMBER
control field 978-3-642-39128-6
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211203023608.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr nn 008mamaa
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130724s2014 gw | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9783642391286
-- 978-3-642-39128-6
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-3-642-39128-6
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number T174.7
072 #7 - SUBJECT CATEGORY CODE
Subject category code TDPB
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code TEC027000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 620.5
Edition number 23
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Malboubi, Majid.
Relator term author.
9 (RLIN) 155880
245 10 - TITLE STATEMENT
Title Gigaseal Formation in Patch Clamping
Medium [electronic resource] :
Remainder of title With Applications of Nanotechnology /
Statement of responsibility, etc by Majid Malboubi, Kyle Jiang.
264 #1 -
-- Berlin, Heidelberg :
-- Springer Berlin Heidelberg :
-- Imprint: Springer,
-- 2014.
300 ## - PHYSICAL DESCRIPTION
Extent XI, 94 p. 81 illus., 65 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content Type Term text
Content Type Code txt
Source rdacontent
337 ## - MEDIA TYPE
Media Type Term computer
Media Type Code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier Type Term online resource
Carrier Type Code cr
Source rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement SpringerBriefs in Applied Sciences and Technology,
International Standard Serial Number 2191-530X
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Chapter 1 Introduction -- Chapter 2 Development of patch clamping -- Chapter 3 Gigaseal formation -- Chapter 4 Effect of roughness on gigaseal formation -- Chapter 5 Effect of hydrophilicIty on gigaseal formation -- Chapter 6 Effect of tip size on gigaseal formation -- Chapter 7 Study of glass micropipettes from tip formation to characterization -- References.
520 ## - SUMMARY, ETC.
Summary, etc This book presents an investigation of gigaseal formation using micro/nanotechnology. The aims of the book are twofold. First, it explains the mechanisms of gigaseal formation using the latest discoveries. Second, it provides practical techniques for frequent formation of high resistance seals. The formation of a high-resistance electrical seal, also known as a gigaseal, between a cell membrane and a glass micropipette tip is essential in patch-clamp experiments. Even though four decades have passed since the introduction of the patch-clamping technique by Neher and Sakmann, gigaseal formation remains an obstacle in developing the high-throughput ion channel screening systems required by the pharmaceutical industry. Here the authors share their latest methods for achieving gigaseal formation and describe techniques that are highly desirable at both research and industrial levels. Nanotechnology has been found to be a powerful tool for studying and modifying glass micropipettes and in tackling the problem of gigaseal formation.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Engineering.
9 (RLIN) 155881
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanotechnology.
9 (RLIN) 799
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedical engineering.
9 (RLIN) 1091
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Engineering.
9 (RLIN) 155881
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Nanotechnology and Microengineering.
9 (RLIN) 155882
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedical Engineering.
9 (RLIN) 1091
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Jiang, Kyle.
Relator term author.
9 (RLIN) 11923
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
9 (RLIN) 25138
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9783642391279
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title SpringerBriefs in Applied Sciences and Technology,
-- 2191-530X
9 (RLIN) 155883
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-3-642-39128-6">http://dx.doi.org/10.1007/978-3-642-39128-6</a>
912 ## -
-- ZDB-2-ENG
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Ebook
956 ## - LOCAL ELECTRONIC LOCATION AND ACCESS (OCLC)
Electronic name Springer

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