Bibliothèque de L'IMIST/CNRST

Thoroughly updated and in a new two-color format, this well- respected text presents the fundamentals of biochemistry and related topics to students pursuing a one- or two-semester course in pre-med biochemistry or medical programs. The second edition is equally applicable to other health-related fields such as clinical chemistry, medical technology or pharmacology. Medical Biochemistry, Fourth Edition, focuses on the foundations and clinically relevant applications of normal human biochemistry and pathology. Abundantly illustrated with four-color plates. Revised chapters on molecular biology reflect the latest research in the field Two color throughout with four color plates Reference quality appendices include practical information on clinical lab parameters used to diagnose a range of diseases.

Includes bibliographical references and index.

Water, Acids, Bases, and Buffers. -- Amino Acids. -- Protein Isolation and Determination of Amino Acid Sequence. -- Three-Dimensional Structure of Proteins. -- Thermodynamics, Chemical Kinetics, and Energy Metabolism. -- Enzymes I: General Properties, Kinetics, and Inhibition. -- Enzymes II: Regulation. -- Enzymes III: Clinical Applications. -- Simple Carbohydrates. -- Heteropolysaccharides I: Glycoproteins and Glycolipids. -- Heteropolysaccharides II: Proteoglycans and Peptidoglycans. -- Gastrointestinal Digestion and Absorption. -- Carbohydrate Metabolism I: Glycolysis and TCA Cycle. -- Electron Transport and Oxidative Phosphorylation. -- Carbohydrate Metabolism II: Gluconeogenesis, Glycogen Synthesis and Breakdown, and Alternative Pathways. -- Carbohydrate Metabolism III: Glycoproteins, Glycolipids, Proteoglycans and Peptidoglycans. -- Proteins and Amino Acid Metabolism. -- Lipids I: Fatty Acids and Eicosanoids. -- Lipids II: Phospholipids, Glycosphingolipids, and Cholesterol. -- Lipids III: Plasma Lipoproteins. -- Muscle and Nonmuscle Contractile Systems. -- Metabolic Homeostasis. -- Molecular Biology I: Nucleic Acids-DNA Structure and Properties. -- Molecular Biology II: DNA Replication, Repair, and Mutagenesis. -- Molecular Biology III: RNA and Protein Synthesis. -- Molecular Biology IV: Regulation of Gene Expression. -- Nucleotide Metabolism. -- Hemoglobin. -- Metabolism of Heme. -- Endocrine Metabolism I: Introduction. -- Endocrine Metabolism II: Hypothalamus and Pituitary. -- Endocrine Metabolism III: Adrenal Glands. -- Endocrine Metabolism IV: Thyroid Gland. -- Endocrine Metabolism V: Reproductive System. -- Molecular Immunology. -- Blood Coagulation and Fibrinolysis. -- Mineral Metabolism. -- Vitamin Metabolism. -- Water, Electrolytes, and Acid-Base Balance.

Ch. 1. Water, acids, bases, and buffers -- Ch. 2. Amino acids -- Ch. 3. Protein isolation and determination of amino acid sequence -- Ch. 4. Three-dimensional structure of proteins -- Ch. 5. Thermodynamics, chemical kinetics, and energy metabolism -- Ch. 6. Enzymes I: general properties, kinetics, and inhibition -- Ch. 7. Enzymes II: regulation -- Ch. 8. Enzymes III: clinical applications -- Ch. 9. Simple carbohydrates -- Ch. 10. Heteropolysaccharides I: glycoproteins and glycolipids -- Ch. 11. Heteropolysaccharides II: proteoglycans and peptidoglycans -- Ch. 12. Gastrointestinal digestion and absorption -- Ch. 13. Carbohydrate metabolism I: glycolysis and TCA cycle -- Ch. 14. Electron transport and oxidative phosphorylation -- Ch. 15. Carbohydrate metabolism II: gluconeogenesis, glycogen synthesis and breakdown, and alternative pathways -- Ch. 16. Carbohydrate metabolism III: glycoproteins, glycolipids, GPI anchors, proteoglycans, and peptidoglycans -- Ch. 17. Protein and amino acid metabolism -- 18. Lipids I: fatty acids and eicosanoids -- Ch. 19. Lipids II: phospholipids, glycosphingolipids, and cholesterol.

Ch. 20. Lipids III: plasma lipoproteins -- Ch. 21. Muscle and nonmuscle contractile systems -- Ch. 22. Metabolic homeostasis -- Ch. 23. Nucleic acid structure and properties of DNA -- Ch. 24. DNA replication, repair, and mutagenesis -- Ch. 25. RNA and protein synthesis -- Ch. 26. Regulation of gene expression -- Ch. 27. Nucleotide metabolism -- Ch. 28. Hemoglobin -- Ch. 29. Metabolism of iron and heme -- Ch. 30. Endocrine metabolism I: introduction -- Ch. 31. Endocrine metabolism II: hypothalamus and pituitary -- Ch. 32. Endocrine metabolism III: Adrenal glands -- Ch. 33. Endocrine metabolism IV: thyroid gland -- Ch. 34. Endocrine metabolism V: reproductive system -- Ch. 35. Molecular immunology -- Ch. 36. Biochemistry of hemostasis -- Ch. 37. Mineral metabolism -- Ch. 38. Vitamin metabolism -- Ch. 39. Water, electrolytes, and acid-base balance.