RNA interference :
Publié par : Wiley, (Hoboken, N.J. :) Détails physiques : 1 online resource (xiv, 310 pages) : color illustrations ISBN :9780470923726; 0470923725.Type de document | Site actuel | Cote | Statut | Date de retour prévue | Code à barres | Réservations |
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Livre | La bibliothèque des Sciences Exactes et Naturelles | 572.88 JOH (Parcourir l'étagère) | Disponible | 0000000024527 |
Includes bibliographical references and index.
RNA interference: What is it? / James A. Birchler -- Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo -- Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris -- Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach -- Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay -- siRNA delivery vehicles / Aliasger K. Salem and Mark A. Behlke -- Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan -- Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins.
"RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects"--Provided by publisher.
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