Bibliothèque de L'IMIST/CNRST

Includes bibliographical references and index.

Cover -- Contents -- Symbols -- Abbreviations and Acronyms -- 1 Object of Analytical Chemistry -- 1.1 Definition of Analytical Chemistry -- 1.2 Repertoire of Analytical Chemistry -- References -- 2 The Analytical Process -- 2.1 Principles of Sampling -- 2.2 Sample Preparation -- 2.3 Principles of Analytical Measurement -- 2.4 Analytical Evaluation -- References -- 3 Signals in Analytical Chemistry -- 3.1 Signals and Information -- 3.2 Analytical Signals -- 3.3 Types and Properties of Analytical Signals -- 3.4 Dimensionality of Analytical Signals and Information -- 3.5 Mathematical Model of Signal Generation -- References -- 4 Statistical Evaluation of Analytical Results -- 4.1 Reliability of Analytical Observations and Measurements -- 4.1.1 Systematic Deviations -- 4.1.2 Random Variations -- 4.2 Uncertainty Concept -- 4.3 Statistical Tests -- 4.3.1 Null Hypotheses -- 4.3.2 Test for Measurement Series -- 4.3.3 Comparison of Standard Deviations -- 4.3.4 Comparison of Measured Values -- 4.4 Reliability of Qualitative Analytical Tests -- 4.5 Statistical Quality Control -- 4.5.1 Quality Criteria for Analytical Results -- 4.5.2 Attribute Testing -- 4.5.3 Sequential Analysis -- 4.5.4 Statistical Quality Control -- References -- 5 Studying Influences and Optimizing Analytical Procedures -- 5.1 Testing the Significance of Influencing Factors -- 5.1.1 Analysis of Variance (ANOVA) -- 5.1.2 Experimental Design -- 5.2 Optimization of Analytical Procedures -- 5.3 Global Optimization by Natural Design -- References -- 6 Calibration in Analytical Chemistry -- 6.1 General Fundamentals of Calibration -- 6.1.1 Fundamental and Experimental Calibration -- 6.1.2 The General Three-Dimensional Calibration Model -- 6.1.3 Regression and Calibration -- 6.2 Single Component Calibration -- 6.2.1 Linear Calibration Model -- 6.2.2 Errors in Linear Calibration -- 6.2.3 Weighted Linear Least Squares Estimation (WLS) -- 6.2.4 Linear Least Squares Fitting in Case of Errors in Both Variables -- 6.2.5 Statistical Tests and Validation of Calibration -- 6.2.6 Alternative Calibration Procedures -- 6.2.7 Nonlinear Calibration -- 6.3 Multisignal Calibration -- 6.4 Multicomponent Calibration -- 6.4.1 Classical Multivariate Calibration -- 6.4.2 Inverse Calibration -- 6.4.3 Validation of Multivariate Calibration -- 6.5 Calibration by Artificial Neural Networks -- References -- 7 Analytical Performance Characteristics -- 7.1 Reliability of Analytical Measurements -- 7.1.1 Precision -- 7.1.2 Precision of Trace Analyses -- 7.1.3 Accuracy and Trueness -- 7.1.4 Remark on the Quantification of Precision, Accuracy and Trueness -- 7.2 Sensitivity -- 7.3 Selectivity and Specificity -- 7.4 Robustness and Ruggedness -- 7.5 Limit Values -- 7.6 Resolving Power -- References -- 8 Presentation, Interpretation and Validation of Analytical Results -- 8.1 Presentation of Analytical Results -- 8.2 Factual Interpretation of Analytical Results -- 8.2.1 Presentation of Results Near.

Delivers a practice-oriented, general guiding theory valid for various methods and techniques of analytical chemistry. Looking to analytical signals and their dependencies, this book discusses and quantifies the important figures of merit characterizing the power of analytical procedures and the reliability of analytical results.