Bibliothèque de L'IMIST/CNRST

Includes bibliographical references and indexes.

v. 1. Psychiatric disorders -- v. 2. Neurological disorders -- v. 3. Reward deficit disorders.

Minimize the number of drug candidates that could later fail in human trials! These three volumes provide a unique examination of how animal models are evolving from "behavioral gut baths" to providing cross-species information relevant to human clinical responses. Each volume provides the views and experiences of leading pre-clinical and clinical investigators who are actively involved in translational research and experimental medicine. Each volume is devoted to specific disorders in three scientific fields: Psychiatric, Neurological, and Reward Deficit. - Clinical, academic, government and industry perspectives fostering integrated communication between principle participants at all stages of the drug discovery process- Critical evaluation of animal and translational models improving transition from drug discovery and clinical development- Emphasis on what results mean to the overall drug discovery process- Exploration of issues in clinical trial design and conductance in each therapeutic area.