RNA turnover in eukaryotes : analysis of specialized and quality control RNA decay pathways /
Collection : Methods in enzymology, 0076-6879 ; . v. 449 Détails physiques : 1 online resource (xliv, 417 pages, [1] leaf of plates) : illustrations (some color) ISBN :9780080923321 (electronic bk.); 0080923321 (electronic bk.); 9780123745842 (electronic bk.); 0123745845 (electronic bk.).
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RNA.
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RNA Precursors
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Laboratory Manuals.
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RNA Stability
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physiology
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Laboratory Manuals.
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Eukaryotic Cells
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metabolism
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Laboratory Manuals.
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RNA, Messenger
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metabolism
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Laboratory Manuals.
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mRNA Cleavage and Polyadenylation Factors
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Laboratory Manuals.
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SCIENCE
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Life Sciences
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Biology.
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SCIENCE
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Life Sciences
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Microbiology.
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Protista.
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RNA.
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Electronic books.
Includes bibliographical references and indexes.
Description based on print version record.
Specific complexes of protein and RNA carry out many essential biological functions, including RNA processing, RNA turnover, RNA folding, as well as the translation of genetic information from mRNA into protein sequences. Messenger RNA (mRNA) decay is now emerging as an important control point and a major contributor to gene expression. Continuing identification of the protein factors and cofactors, and mRNA instability elements responsible for mRNA decay allow researchers to build a comprehensive picture of the highly orchestrated processes involved in mRNA decay and its regulation. * Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway * Expert researchers introduce the most advanced technologies and techniques * Offers step-by-step lab instructions, including necessary equipment and reagents.
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