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Protein engineering for therapeutics. Part A /

Collection : Methods in enzymology ; . v. 502 Détails physiques : 1 online resource : illustrations (some color) ISBN :9780123914743 (electronic bk.); 0123914744 (electronic bk.).
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Exemplaires : http://www.sciencedirect.com/science/book/9780124160392

"The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Antibodies, Protein conjugates, Peptides, Enzymes and Scaffolds."--Provided by publisher.

Simplified synthetic antibody libraries / Saravanan Rajan, Sachdev S. Sidhu -- Generation of dual-variable-domain immunoglobulin molecules for dual-specific targeting / Jijie Gu, Tariq Ghayur -- Discovery of internalizing antibodies to tumor antigens from phage libraries / Yu Zhou, James D. Marks -- Optimizing properties of antireceptor antibodies using kinetic computational models and experiments / Brian D. Harms ... [and others] -- Cell-specific siRNA delivery by peptides and antibodies / Sang-Kyung Lee ... [and others] -- Conjugation of anticancer drugs through endogenous monoclonal antibody cysteine residues / Robert P. Lyon ... [and others] -- Building and characterizing antibody-targeted lipidic nanotherapeutics / Dmitri B. Kirpotin ... [and others] -- Cell-targeting fusion constructs containing recombinant gelonin / Mi-Ae Lyu ... [and others] -- Fusions of elastin-like polypeptides to pharmaceutical proteins / Wafa Hassouneh, Sarah R. MacEwan, Ashutosh Chilkoti -- Oral enzyme therapy for celiac sprue / Michael T. Bethune, Chaitan Khosla -- Rational design and evaluation of mammalian ribonuclease cytotoxins / Jo E. Lomax, Chelcie H. Eller, Ronald T. Raines -- Engineering reduced-immunogenicity enzymes for amino acid depletion therapy in cancer / Jason R. Cantor ... [and others].

Includes bibliographical references and index.

Description based on print version record.

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