Bibliothèque de L'IMIST/CNRST

Includes bibliographical references.

Stem cells and cellular pedigrees : a conceptual introduction / Markus Loeffler and Christopher S. Potten -- Stem cells and founder zones in plants, particularly their roots / Peter W. Barlow -- The stem cell concept applied to shoot meristems of higher plants / Dennis Francis -- Skeletal muscle stem cells : function and potential role in therapy / Diana J. Watt and Gareth E. Jones -- Cell progenitors in the neural crest / Catherine Dulac and Patrizia Cameron-Curry -- Phenotypic diversity and lineage relationships in vascular endothelial cells / Ana M. Schor, Seth L. Schor and Enrique Arciniegas -- Mammary stem cells in normal development and cancer / Philip S. Rudland, Roger Barraclough, David G. Fernig and John A. Smith -- Liver stem cells / J.W. Grisham and Snorri S. Thorgeirsson -- Regulation of proliferation and differentiation of stem cells in the male germ line / Dirk G. de Rooij and Federica M.F. van Dissel-Emiliani -- Stem cell repertoire in the intestine / Nicholas A. Wright -- Keratinocyte stem cells of cornea, skin and hair follicles / Stanley J. Miller, Robert M. Lavker and Tung-Tien Sun -- Tumour stem cells / Johann Kummermehr and Klaus-Rüdiger Trott -- Biology of the haemopoietic stem cell / Brian I. Lord -- Growth factors and the regulation of haemopoietic stem cells / Clare M. Heyworth, Nydia G. Testa, Anne-Marie Buckle and Anthony D. Whetton -- Haematopoietic stem cells for gene therapy / Jan A. Nolta and Donald B. Kohn.

Stem cells are relatively undifferentiated cells which are the permanent lineage ancestor cells of tissues. Newly developed molecular biological techniques and probes have made possible dramatic advances in our ability to study the lineage development of stem cells. A major impetus to develop these techniques has been to identify specific stem cells for gene therapy purposes. The role that stem cells play in the development of cancer is also an important area. This book provides up-to-date reviews on a wide variety of stem cell systems by world experts. Chapters range from descriptions of the current knowledge of the biology of stem cells, to current molecular biological approaches and clinical implications. Oncologists and cell biologists will find this book of particular interest. It will also be usefule to radiobiologist, biotechnologists, and gene therapists. Key Features * Provides reviews of stem cell systems by world experts * Covers stem cell biology in plants, invertebrates, and mammals * Presents clinical implications of stem cell differentiation.

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