Bibliothèque de L'IMIST/CNRST

Based on topics presented at the Annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the Biennial China-Japan Drug Design and Development conference, the topics in this volume cover almost every procedure and subdiscipline in the SAR discipline. They are categorized in three sections. Section one includes topics illustrating newer methodologies relating to ligand-receptor, molecular graphics and receptor modelling as well as the three-dimensional (Q)SAR examples with the active analogue approach and the comparative molecular field analysis. In section 2 the hydrophobicity parameters, log P (1-octanol/water) for compound series of medicinal-chemical interest are analysed physico-organic chemically. Section 3 contains the examples based on the traditional Hansch QSAR approach. A variety of methodologies and procedures are presented in this single volume, along with their methodological philosophies.

"Based on topics presented at the annual Japanese (Quantitative) Structure-Activity Relationship Symposium and the biennial China-Japan Drug Design and Development Conference."

Includes bibliographical references and index.

Description based on print version record.

Front Cover; QSAR and Drug Design: New Developments and Applications; Copyright Page; Preface; Contents; Section I: Three-Dimensional Structure-Based Drug Design, Molecular Modelling and Three-Dimensional QSAR; Section II: Quantitative Structure-Parameter Analyses and Database-Oriented and Newer Statistical (Q)SAR Procedures and Drug Design; Sevtion III: Traditional QSAR and Drug Design.; Subject index;