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Genomics :

Publié par : Wiley-Blackwell, (Chichester :) Détails physiques : xvi, 333 pages ISBN :9780470711675; 0470711671; 9780470711576; 0470711574; 9780470711620; 0470711620. Année : 2011
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Livre La bibliothèque des Sciences Exactes et Naturelles
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Includes bibliographical references and index.

Front Matter -- Colour Plates -- High-Resolution Analysis of Genomic Copy Number Changes / Mario Hermsen, Jordy Coffa, Bauke Ylstra, Gerrit Meijer, Hans Morreau, Ronald van Eijk, Jan Oosting, Tom van Wezel -- Identification of Polymorphic Markers for Genetic Mapping / Daniel C Koboldt, Raymond D Miller -- Genotyping and LOH Analysis on Archival Tissue using SNP Arrays / Ronald van Eijk, Anneke Middeldorp, Esther H Lips, Marjo van Puijenbroek, Hans Morreau, Jan Oosting, Tom van Wezel -- Genetic Mapping of Complex Traits / Nancy L Saccone -- RNA Amplification Strategies: Toward Single-Cell Sensitivity / Natalie Stickle, Norman N Iscove, Carl Virtanen, Mary Barbara, Carolyn Modi, Toni Di Berardino, Ellen Greenblatt, Ted Brown, Neil Winegarden -- Real-Time Quantitative RT-PCR for mRNA Profiling / Stephen A Bustin, Tania Nolan -- Gene Expression in Mammalian Cells / F̌lix Recillas-Targa, Georgina Guerrero, Mart̕n Escamilla-del-Arenal, Ȟctor Rinc̤n-Arano -- Using Yeast Two-Hybrid Methods to Investigate Large Numbers of Binary Protein Interactions / Panagoula Charalabous, Jonathan Woodsmith, Christopher M Sanderson -- Prediction of Protein Function / Hon Nian Chua -- Elucidating Gene Function through use of Genetically Engineered Mice / Mary P Heyer, C̀tia Feliciano, Jôo Peca, Guoping Feng -- Delivery Systems for Gene Transfer / Charlotte Lawson, Louise Collins -- Gene Therapy Strategies: Constructing an AAV Trojan Horse / M Ian Phillips, Edilamar M de Oliveira, Leping Shen, Yao Liang Tang, Keping Qian -- An Introduction to Proteomics Technologies for the Genomics Scientist / David B Friedman -- Index.

Genomics research has made significant advances in recent years. In this book, a team of internationally-renowned researchers share the most up-to-date information in a field that has in recent years switched emphasis from gene identification to functional genomics and the characterization of genes and gene products. This volume approaches this complex subject with a broad perspective to supply the reader with a vital overview of genomics and its derivative fields, with a focus on pivotal issues such as data analysis. Expansive and current, this book is a comprehensive research guide that desc.

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