TY - BOOK AU - Kalden,,Joachim R. AU - Herrmann,,Martin TI - Apoptosis and autoimmunity: from mechanisms to treatments SN - 3527304428 U1 - 571.973 PY - 2003/// CY - [S.l.] PB - Wiley-VCH KW - Allergies KW - Biology, life sciences KW - Clinical & internal medicine KW - Medical KW - Medical / Nursing KW - Immunology KW - Life Sciences - Cytology KW - Medical / Immunology KW - SCIENCE / Life Sciences / Cytology KW - Apoptosis KW - Autoimmune diseases KW - Autoimmunity KW - Clinical Medicine: Professional N1 - This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies ER -