TY - BOOK AU - Mevorach,Dror ED - New York Academy of Sciences. TI - Clearance of dying cells in healthy and diseased immune systems T2 - Annals of the New York Academy of Sciences SN - 9781573317979 AV - QH671 U1 - 616.0799 22 PY - 2010/// CY - Boston, Mass. PB - Published by Blackwell Pub. on behalf of the New York Academy of Sciences KW - Cell death KW - Physiology KW - immunology KW - physiology KW - etiology KW - Immune system KW - Immunologic diseases KW - Apoptosis KW - Phagocytosis KW - Cell Death KW - Immune System KW - Immune System Diseases N1 - "The mode of death and the clearance of dying cells has a tremendous impact on immune tolerance and alters the clearance of dying cells, which may lead to autoimmunity and persistent inflammation. Inflammatory and "dangerous" modes of death influence the process of clearance and have a crucial role in cancer and interaction with organisms that may mimic molecules appearing dying cells. These observation lead to the need of an exchange emphasizing the mammalian immune system in the context of diseases, such as inflammatory and autoimmune diseases, cancer, and infections. This volume explores a number of topics in this area including mechanisms of tolerance induction by dying cells; mechanisms of danger induction by dying cells; infection and clearance of dying cells; autoimmunity, inflammation and clearance of dying cells; clearance of dying cells in cancer; and clearance of dying cells in the pathogenesis of additional diseases."--Publisher website; Papers presented at a conference entitled "Clearance of Dying Cells in a Healthy and Diseased Immune System" held May 9-11, 2010 in Jerusalem, Israel; Includes bibliographical references; Intravenous apoptotic cell infusion as a cell-based therapy toward improving hematopoietic cell transplantation outcome ER -