TY  - BOOK
AU  - Gulbins,Erich
AU  - Petrache,Irina
ED  - SpringerLink (Online service)
TI  - Sphingolipids: Basic Science and Drug Development
T2  - Handbook of Experimental Pharmacology,
SN  - 9783709113684
AV  - RM1-950 
U1  - 615 23
PY  - 2013///
CY  - Vienna
PB  - Springer Vienna, Imprint: Springer
KW  - Medicine
KW  - Cancer research
KW  - Molecular biology
KW  - Pharmacology
KW  - Oncology
KW  - Cell biology
KW  - Cell membranes
KW  - Biomedicine
KW  - Pharmacology/Toxicology
KW  - Membrane Biology
KW  - Cancer Research
KW  - Molecular Medicine
KW  - Cell Biology
N1  - Preface -- Part 1. Basic mechanisms -- Part 2. Drug development
N2  - Sphingolipids are lipid components of the plasma membrane in eukaryotic cells. They have an important function in signaling mechanisms in the cell. This book on sphingolipids provides insights into the basics of sphingolipid biology and drug development, with a particular emphasis on the sphingolipid derivative ceramide. In the first part basic functions of sphingolipids are described, as well as the genetics of important enzymes, sphingolipid metabolism and synthesis. The second part of this first volume focuses on drug development and pharmacology. The book is intended for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians working in pharmacology, oncology, cardiology, neurology and infectious disease. Together with Volume 216 by the same editors, the collection represents a unique, comprehensive work on sphingolipids, providing information on both sphingolipids’ basic biology (including synthesis, metabolism and cell biology) and their important function in a (patho-)physiological context
UR  - http://dx.doi.org/10.1007/978-3-7091-1368-4
ER  -