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Motor neuron disorders /

Autres auteurs : Shaw, Pamela J. | Strong, Michael J.
Collection : Blue books of practical neurology ; . 28 Détails physiques : 1 online resource (xvi, 569 pages [10] pages of plates) : illustrations. ISBN :9780702038877; 0702038873.
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Includes bibliographical references and index.

SECTION 1: KEY PRINCIPLES IN THE CLINICAL DIAGNOSIS, PATHOLOGY, AND INVESTIGATION OF MOTOR NEURON DISORDERS -- Clinical principles in the diagnosis of motor neuron disorders / Michael Swash -- Pathology of motor neuron disorders / Steven Wharton, Paul G. Ince -- Neurophysiological investigation of motor neuron disorders / Kerry R. Mills -- Neuroimaging in motor neuron disorders / Erik P. Pioro -- SECTION 2: AMYOTROPHIC LATERAL SCLEROSIS/MOTOR NEURON DISEASE -- Clinical aspects of sporadic amyotrophic lateral sclerosis/motor neuron disease / Lewis P. Rowland -- Cognitive impairment in the motor neuron disorders / Michael J. Strong, Catherine Lomen-Hoerth, Wenchang Yang -- Epidemiology of amyotrophic lateral sclerosis/motor neuron disease / Carmel Armon -- Genetic aspects of amyotrophic lateral sclerosis/motor neuron disease / Peter M. Andersen -- Cellular biological effects of copper/zinc superoxide dismutase mutations / Andrew J. Grierson, Pamela J. Shaw -- Excitotoxicity and oxidative stress in pathogenesis of amyotrophic lateral sclerosis/motor neuron disease / Philip Van Damme, Ludo Van Den Bosch, Wim Robberecht -- Mitochondrial dysfunction in amyotrophic lateral sclerosis / Clare A. Wood-Allum, Pamela J. Shaw -- Cytoskeletal abnormalities in amyotrohpic lateral sclerosis/motor neuron disease / Janice Robertson, Jean-Pierre Julien -- Role of microglia in amyotrophic lateral sclerosis / Michael J. Strong, Weiyan Wen -- Cell death pathways in amyotrophic lateral sclerosis / Serge Przedborski, Peter G.H. Clarke -- Factors underlying the selective vulnerability of motor neurons to neurodegeneration / Heather D. Durham -- SECTION 3: OTHER MOTOR NEURON DISORDERS -- Spinal muscular atrophy / Kevin Talbot, Kay E. Davies -- Kennedy's disease / Charlotte J. Sumner, Kenneth H. Fischbeck -- Hereditary spastic paraparesis / Christohper J. McDermott, Pamela J. Shaw -- SECTION 4: THERAPEUTICS OF MOTOR NEURON DISORDERS -- Quality of life and psychosocial aspects of care of patients with amyotrophic lateral sclerosis / Deborah F. Gelinas, Robert G. Miller -- Symptom control in amyotrophic lateral sclerosis/motor neuron disease / Johanna Anneser, Gian Domenico Borasio -- Disease-modifying therapies in motor neuron disorders: the present position and potential future developments / Martin R. Turner, P. Nigel Leigh.

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