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Evans,, G.O.
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Animal clinical chemistry
a primer for toxicologists
Publication :
[S.l.] CRC Press 1996 . 224 p. , By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science. 25 cm.
Date :
1996
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Biopharmaceutics applications in drug development
Publication :
[S.l.] Springer 2007 . 402 p. , In the last two decades, the discipline of biopharmaceutics has undergone considerable advances, particularly with regard to bioavailability and bioequivalence as they relate to product quality and regulatory standards of approval. Textbooks in the field have not been able to keep up with the growth of current and emerging applications of regulatory aspects of biopharmaceutics. Biopharmaceutics Applications in Drug Development fills this gap. This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development. 24 cm.
Date :
2007
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Toxic plants dangerous to humans and animals /
par
Bruneton, Jean.
Publication :
[S.l.] : Lavoisier, 2000 . 545 p. ; , Physicians, pharmacists and veterinarians who deal with accidental plant ingestions on a daily basis are largely ill-prepared to manage such cases. Reliable information is therefore scarce. "Toxic Plants" seeks to meet this need. Part 1 lists the common causes of plant induced incidents and accidents in humans. The risks are described, in particular those inherent to herbal drugs. Plant identification and medical treatment are discussed , as well as the specifics of animal poisoning, paying special attention to pets. Part 2 is a detailed discussion of the plant species, most frequently implicated. It includes the circumstances of the intoxication, symptoms, proposed treatment, toxic doses, and also elements of diagnosis, toxin identification and toxic mechanisms. This book contains more than 1300 literature references and the most recent statistics. Four dozen botanical families are classified alphabetically with over 350 plant species including 100 plant monographs and numerous illustrations. This highly educational tool gives a complete picture of the toxic potential of higher plants. 25 cm.
Date :
2000
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