Catalogue Bibliothèque de L'IMIST/CNRST › Résultats de la recherche pour 'ccl=su:Chemistry'

Medicinal chemistry of anticancer drugs par Avendano, Carmen. Publication : Amsterdam ; Boston Elsevier Science 2008 . 442 p. d24 cm. , Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

		ADMET for medicinal chemists a practical guide / Publication : Hoboken, N.J : John Wiley & Sons, 2011 . 1 online resource (xx, 498 p.) : Date : 2011 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Aggregation of therapeutic proteins Publication : Hoboken Wiley 2010 . xxii, 486 p. , This book gives pharmaceutical scientists an up-to-date resource on protein aggregation and its consequences, and available methods to control or slow down the aggregation process. While significant progress has been made in the past decade, the current understanding of protein aggregation and its consequences is still immature. Prevention or even moderate inhibition of protein aggregation has been mostly experimental. The knowledge in this book can greatly help pharmaceutical scientists in the development of therapeutic proteins, and also instigate further scientific investigations in this area. This book fills such a need by providing an overview on the causes, consequences, characterization, and control of the aggregation of therapeutic proteins. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Analytical method validation and instrument performance verification / Publication : Hoboken, N.J. : John Wiley & Sons, 2004 . x, 303 p. : 24 cm. Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Chemical library design / Publication : New York, NY : Humana Press, 2011 . x, 362 pages : 27 cm. Date : 2011 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Development of therapeutic agents handbook / Publication : Hoboken, N.J. : John Wiley and Sons, 2012 . xvii, 1258 pages : 29 cm. Date : 2012 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization / par Kerns, Edward Harvel, Publication : Amsterdam ; \| Boston : Academic Press, 2008 . xix, 526 pages, [2] pages of plates : 27 cm Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Flow cytometry in drug discovery and development / Publication : Hoboken, N.J. : Wiley, 2011 . xviii, 341 pages : , "This book covers the unique application of flow cytometry in drug discovery and development. The first section includes two introductory chapters, one on flow cytometry and one on biomarkers, as well as a chapter on recent advances in flow cytometry. The second section focuses on the unique challenges and added benefits associated with the use of flow cytometry in the drug development process. The third section contains a single chapter presenting an in depth discussion of validation considerations and regulatory compliance issues associated with drug development"--Provided by publisher. 24 cm. Date : 2011 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Handbook of modern pharmaceutical analysis / Publication : Amsterdam ; \| Boston : Elsevier/Academic Press, 2011 . xv, 582 pages, [4] pages of plates : , Previous edition: 2001. 26 cm. Date : 2011 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Hplc for pharmaceutical scientists par Kazakevich,, Yuri V. Publication : [S.l.] Wiley-Interscience 2007 . 1140 p. , HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Medicinal chemistry of anticancer drugs par Avendano, Carmen. Publication : Amsterdam ; Boston Elsevier Science 2008 . 442 p. d24 cm. , Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		New avenues to efficient chemical synthesis : emerging technologies / Publication : Berlin ; \| New York : Springer, 2007 . xiv, 240 p. : 22 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Optimizing the "drug-like" properties of leads in drug discovery / Publication : New York, NY : Springer, 2006 . x, 512 p. : 27 cm + Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Profiles of drug substances, excipients, and related methodology . Vol. 34 / Publication : . 1 online resource (ix, 349 pages) , Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs * Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others * Meets the information needs of the drug development community. Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Sterile filtration. Publication : [S.l.] : Springer, 2006 . 203 p. ; , 1 R. Levy: Types of Filtration.- 2 T. Meltzer: Modus of Filtration.- 3 O.W. Reif: Microfiltration Membranes: Characteristics and Manufacturing.- 4 M. Jornitz: Filter Constructions and Design.- 5 R. Madsen: Filter Validation.- 6 M. Jornitz: Integrity Testing.- 24 cm. Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		The Practice of Medicinal Chemistry. par Wermuth, Camille Georges. Publication : Burlington : Elsevier, 2008 . 1 online resource (982 pages) Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (2), Réserver Ajouter au panier (Supprimer)
		Capillary electrophoresis methods for pharmaceutical analysis / Publication : Amsterdam ; \| Boston : Elsevier/Academic Press, 2008 . xvi, 529 pages : Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (2), Réserver Ajouter au panier (Supprimer)
		Profiles of drug substances, excipients, and related methodology . Vol. 34 / Publication : . 1 online resource (ix, 349 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780123743404, Ajouter au panier (Supprimer)
		Profiles of drug substances, excipients and related methodology . Volume 35 / Publication : . 1 online resource (ix, 396 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780123808844, Ajouter au panier (Supprimer)
		Profiles of drug substances, excipients, and related methodology. Volume 36 / Publication : . ix, 388 pages : 23 cm. Disponibilité : http://www.sciencedirect.com/science/book/9780123972200, Ajouter au panier (Supprimer)
		COSMO-RS : from quantum chemistry to fluid phase thermodynamics and drug design / par Klamt, Andreas. Publication : . 1 online resource (xi, 234 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780444519948, Ajouter au panier (Supprimer)

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