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Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization / par Kerns, Edward Harvel, Publication : Amsterdam ; | Boston : Academic Press, 2008 . xix, 526 pages, [2] pages of plates : 27 cm Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Drugs : from discovery to approval / par Ng, Rick. Publication : Hoboken, N.J. : Wiley-Liss, 2004 . xii, 355 p. : 24 cm. Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Medicinal applications of coordination chemistry par Jones, Chris J. Publication : [S.l.] Royal Society of Chemistry 2007 . 370 p. , Metals in pharmaceuticals have played an increasingly important role in medicine over the last century, particularly in cancer therapy and diagnostic imaging methods. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. Medicinal Applications of Coordination Chemistry begins with a brief historical review and an introduction to the chemistry of d- and f- block metals. Subsequent sections discuss metallodrugs for a number of different applications, the design of new drugs and the relationship between structure and function. Key sections include diagnostic applications of metal compounds in anatomical and functional imaging, and therapeutic applications of metals compounds. This book is ideal for researchers in academia and industry and comes complete with examples of real life applications. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Medicinal chemistry of anticancer drugs par Avendano, Carmen. Publication : Amsterdam ; Boston Elsevier Science 2008 . 442 p. d24 cm. , Antitumour chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells. These therapies are in their infancy, but they hold promise of more effective therapies with fewer side effects. Resistance to antitumour drugs is another important but normally neglected field. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumour drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumour agents, aiming at the rationalization of the action of this type of drugs, which would allow the design of new active structures. * Presents information in a clear and concise way using a large number of figures * Historical background provides insights on how the process of drug discovery in the anticancer field has evolved * Extensive references to primary literature. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Profiles of drug substances, excipients, and related methodology . Vol. 34 /   Publication : . 1 online resource (ix, 349 pages) , Volumes in this widely revered series present comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. This organizational structure meets the needs of the pharmaceutical community and allows for the development of a timely vehicle for publishing review materials on this topic. The scope of the Profiles series encompasses review articles and database compilations that fall within one of the following six broad categories: Physical profiles of drug substances and excipients; Analytical profiles of drug substances and excipients; Drug metabolism and pharmacokinetic profiles of drug substances and excipients; Methodology related to the characterization of drug substances and excipients; Methods of chemical synthesis; and Reviews of the uses and applications for individual drug substances, classes of drug substances, or excipients. * Presents comprehensive reviews covering all aspects of drug development and formulation of drugs * Profiles creatine monohydrate and fexofenadine hydrochloride, as well as five others * Meets the information needs of the drug development community. Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
The Practice of Medicinal Chemistry. par Wermuth, Camille Georges. Publication : Burlington : Elsevier, 2008 . 1 online resource (982 pages) Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (2),

Essentials of organic chemistry : for students of pharmacy, medicinal chemistry and biological chemistry / par Dewick, Paul M. Publication : Chichester, West Sussex, England ; | Hoboken, N.J. : J. Wiley, 2006 . xiv, 696 pages : , Includes index. 26 cm Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

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