Bibliothèque de L'IMIST/CNRST

The volumes in this series include contemporary techniques significant to a particular branch of neuroscience. They are an invaluable aid to the student as well as the experienced researcher not only in developing protocols in neuroscience but in disciplines where research is becoming closely related to neuroscience. Each volume of Methods in Neurosciences contains an index, and each chapter includes references. Dr. Conn became Editor-in-Chief of the series beginning with Volume 15, so each subsequent volume could be guest-edited by an expert in that specific field. This further strengthens the depth of coverage in Methods in Neurosciences for students and researchers alike. Comprehensive protocols included for: * Enzymes involved in the activation of bioactive peptidases and proteins * Prohormone/neuropeptide processing pathways * Enzymes involved in peptide metabolism * Posttranslational processing enzymes.

Molecular Approaches for the Study of Intracellular Processing Enzymes: -- N.G. Seidah, Molecular Strategies for Identifying Processing Enzymes. -- M.K.-H. Schefer and R. Day, In Situ Hybridization Techniques to Map Processing Enzymes. -- M. Zheng and J.E. Pintar, Analysis of Ontogeny of Processing Enzyme Gene Expression and Regulation. -- J.K. VanSlyke, L. Thomas, and G. Thomas, Use of Vaccinia Virus Vectors to Study Neuropeptide Processing. -- I. Lindberg and Y. Zhou, Overexpression of Neuropeptide Precursors and Processing Enzymes. -- R.E. Mains, Use of Antisense RNA to Block Peptide-Processing Enzyme Expression. -- Immunological and Biochemical Approaches to the Study of Peptide-Processing Pathways: -- A.I. Smith and R.A. Lew, Combination of High-Performance Liquid Chromatography and Radioimmunoassay for Characterization of Peptide-Processing Pathways. -- S.R. Crosby, Development and Use of Two-Site Immunometric Assays for Examining Peptide-Processing Pathways. -- P. Cohen, M. Rholam, and H. Boussetta, Methods for Identification of Neuropeptide-Processing Pathways. -- H. Gainer, M.O. Lively, and M. Morris, Immunological and Related Techniques for Studying Neurohypophyseal Peptide-Processing Pathways. -- R.G. Allen and J. Stack, Approaches to Assessing Ontogeny of Processing Enzymes. -- R.A. Lew and A.I. Smith, Measurement, Distribution, and Subcellular Localization of Peptide-Amidating Activity. -- L.D. Fricker, Methods for Studying Carboxypeptidase E. -- T.J. Opgenorth, S. Kimura, and J.R. Wu-Wong, Characterization of Endothelin-Converting Enzymes. -- A. Shulkes, In Vivo Approaches for Studying Peptide Processing. -- Identification and Characterization of Extracellular Processing Enzymes in the Central Nervous System: -- J.R. McDermont and A.M. Gibson, Identification and Characterization of Central Nervous System Peptidase Activities. -- M.J. Glucksman and J.L. Roberts, Strategies for Characterizing, Cloning, and Expressing Soluble Endopeptidases. -- D.H. Small, G. Reed, S.J. Fuller, A. Weidemann, K. Beyreuther, and C.L. Masters, Proteolytic Processing and Amyloid Protein Precursor of Alzheimers Disease. -- D.J. Campbell, A.C. Lawrence, A. Kladis, and A.-M. Duncan, Strategies for Measurement of Angiotensin and Bradykinin Peptides and Their Metabolites in Central Nervous System and Other Tissues. -- A.J. Turner and K. Barnes, Distribution and Roles of Endopeptidase 24.11. -- F. Checler, P. Dauch, H. Barelli, V. Dive, Y. Masuo, B. Vincent, and J.P. Vincent, Identification and Distribution of Endopeptidase 24.16 in the Central Nervous System. -- S.Y. Chai and F.O. Mendelsohn, Autoradiographic Techniques to Map Angiotensin-Converting Enzyme in Brain and Other Tissues. -- Index.

Includes bibliographical references and index.

Description based on print version record.