IMIST


Exemplaires : http://www.sciencedirect.com/science/book/9780121016258

Includes bibliographical references and index.

Nucleic acid and protein sequence databases / G. Williams -- Phenotype, mutation and genetic linkage databases and their links to sequence databases / R. Cotton -- DNA composition, codon usage and exon prediction / R. Guigó -- Properties of amino acids in sequences / W.R. Taylor -- Sequence comparison / M. Gribskov -- Simple repetitive sequences in DNA databanks / J. Epplen and E.J.M. Santos -- Gene feature identification / P. Bucher -- Multiple sequence alignment / D. Higgins -- On-line resources for RNA science / K. Triman -- Predicting the evolution, structure and function of proteins from sequence information / C.P. Ponting and D.J. Blake -- Structural databases / D. Jones -- PKR : the protein kinase resource / M. Gribskov, P. Bourne and C.M. Smith -- Gene expression databases / R. Baldock and D. Davidson -- Using EcoCyc databse / P.D. Karp.

Computer access is the only way to retrieve up-to-date sequences and this book shows researchers puzzled by the maze of URLs, sites, and searches how to use internet technology to find and analyze genetic data. The book describes the different types of databases, how to use a specific database to find a sequence that you need, and how to analyze the data to compare it with your own work. The content also covers sequence phenotype, mutation, and genetic linkage databases; simple repetitive DNA sequences; gene feature identification; and prediction of structure and function of proteins from sequence information. This book will be invaluable to those starting a career in life sciences research as well as to established researchers wishing to make full use of available resources. Key Features * Describes a wide range of databases: DNA, RNA, protein, pathways, and gene expression * Enables readers to access the information they need from databases on the web * Includes a directory of URLs for easy reference * Invaluable for those starting a career in life sciences research and also for established researchers wishing to make full use of available resources.

Description based on print version record.

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