Bibliothèque de L'IMIST/CNRST

The fourth edition of The Cytokine Handbook provides an encyclopedic coverage of the molecules that induce and regulate immune responses. Now expanded to two volumes, co-edited by Michael T Lotze, and written by over 120 international experts, the scope of the book has been broadened to include a major emphasis on the clinical applications of cytokines. The early chapters discuss individual cytokines, chemokines and receptors. Additional chapters discuss the clinical implications and applications of cytokines, including cytokine gene transfer, antisense therapy and assay systems. This book is essential for researchers and clinicians interested in cytokines, including anyone working in cancer biology, transplantation, infectious diseases, autoimmunity or bioinformatics. Key Features * Covers all main cytokines and chemokines * Written by experts * Up-to-date- includes detailed referencing accessing current, modern literature and reflects the newest findings from the human genome * The new edition has been thoroughly revised and extended (now 2 volumes) as compared to the last edition, including new co-editor (MTL), new authors, new hot topics and new chapters * Includes major emphasis on clinical applications * Extensively illustrated with tables and figures.

Volume 1 -- Preface -- Foreward -- Section I Basic Cytokine Biology -- 1Cytokines Overview -- 2Cytokine Genetics -- 3The Phylogeny of Cytokines -- 4Cytokine Signalling -- Section II The Cytokines and Chemokines -- Subsection A. The Hematopoietin Family Members -- 5Growth Hormone and its Receptors -- 6Prolactin -- 7Erythropoietin -- 8Interleukin 2 -- 9Interleukin 3 -- 10Interleukin 4 -- 11Interleukin 5 -- 12Interleukin 6 -- 13Interleukin 7 -- 14Interleukin 9 -- 15Interleukin 11 -- 16Interleukin 12 Family: IL-12 -- 17Interleukin 13 -- 18Interleukin 15 and Interleukin 21 -- 19Interleukin 16 -- 20Interleukin 17 -- 21Granulocyte-Macrophage -- 22Granulocyte Colony-Stimulating Factor and its Receptor -- 23M-CSF Subsection B. The Interferon Family Members -- 24Type I Interferons -- 25Interferon-g -- 26Interleukin 10 -- 27Interleukins 19, 20, 22, 24 and 26 -- Volume II. -- Subsection C. The beta trefoil cytokines -- 28Interleukin 1 a and b -- 29Interleukin 1 Receptor Antagonist -- 30Novel Interleukin-1 Homologues -- 31Interleukin 18 -- 32The Fibroblast Growth Factors -- 33The Hepatocyte Growth Factor The HGF Receptor, MET -- 34Toll-like Receptors: The Origins of Inflammation -- 35Lymphotoxins -- 36Tumor Necrosis Factor -- 37TRAIL/apo2L -- 38RANK-L : Receptor Activator of NF-kB Ligan -- 39CD95L/FasL its receptor CD95 (APO-1/Fas) -- 40HMGB-1/Amphoterin -- 41EGF Family Ligand -- 42FLT3 Ligand -- 43Stem Cell Factor -- 44Vascular Endothelial Growth Factor -- 45Macrophage Migration Inhibitory Factor (MIF)46Interleukin-8 and other CXC Chemokines -- 47C-C Chemokines -- 48Fractalkine-A Cell Surface Chemokines -- 49Transforming Growth Factor b -- 50Inhibin/Activin Family -- 51Bone Morphogenic Proteins -- Section III. Clinical Application of Cytokines and Cytokine Inhibition -- 52Autoimmunity and Cytokines: Pathogenesis and Therapy -- 53Cytokines and Cancer Caligiuri -- 54Interferon alpha: biology, pharmacology, and therapy for chronic viral hepatitis -- 55Haemopoietic Cytokines -- 56Antiangiogenesis -- 57Transplantation -- 58Cytokines and Asthma -- 59Cytokine Gene Transfer -- 60Antisense Therapy -- 61Assays for Cytokines.

Includes bibliographical references and index.

Description based on print version record.

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Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002. MiAaHDL

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