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Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Détails physiques : VIII, 588 p. online resource. ISBN :9781461447290.
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Exemplaires : http://dx.doi.org/10.1007/978-1-4614-4729-0

An Introduction to CNS-resident Microglia: Definitions, Assays and Functional Roles in Health and Disease -- Astrocyte-neuron Communications -- Neuroimmune Modulation of Synaptic Function -- Neuroimaging and Clinical Studies on Brain-Immune Interactions -- Mechanisms of Stress-Dependent Neuroinflammation and their Implications for Understanding Consequences of Alcohol Exposure -- Mood Disorders and Immunity -- Neuroimmune Cross Talk and HIV-Associated Neurocognitive Disorders -- Innate Immune Signaling and Alcoholism -- Role of TOLL-Like Receptor 4 in Alcohol-Induced Neuroinflammation and Behavioral Dysfunctions -- Prenatal Alcohol Exposure: Impact on Neuroendocrine-Neuroimmune Networks -- Neuroimmune Mechanisms of Glia and Their Interplay with Alcohol Exposure across the Lifespan -- Alcohol-chemokine Interaction and Neurotransmission -- Neuroimmune Genes and Alcohol Drinking Behavior -- Immune Responses in HIV Infection, Alcoholism, and Aging: A Neuroimaging Perspective -- Effects of Morphine and Alcohol on the Hypothalamic-pituitary-adrenal Axis, Immunity, and Cognitive Behavior -- Alcohol Abuse, HIV-1 and Hepatitis C Infection -- Therapeutic Strategies to Treat Alcohol-related Disorders Targeting Central Immune Signaling -- Alcohol and the Neuroimmune Response: Current Status and Future Directions.

Rapid advances in understanding neural-immune interactions have far reaching impact on research in many areas of neuroscience. It is becoming increasingly clear that neuroimmune factors modulate a wide range of brain functions and play an important role in development, normal brain function, and CNS dysfunctions, including neurodegenerative diseases, neuropsychiatric disorders and addiction. “Neural–Immune Interaction in Brain Function and Alcohol Related Disorders” integrates emerging knowledge on neural-immune interactions with related key discoveries in alcohol research to provide a comprehensive overview of neuroimmune system in brain function and behavior associated with alcohol use disorders.  Readers will benefit from cutting edge insights provided by outstanding, active researchers in the fields of neuroimmune research and alcohol use disorders.

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