Bibliothèque de L'IMIST/CNRST

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Bone marrow and stem cell transplantation.   Publication : [S.l.] Humana Press 2007 . 234 p. , This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up. With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Metastasis of breast cancer / par Mansel,, R.E. Publication : [S.l.] : Springer, 2007 . 435 p. ; , Metastasis (spread of cancer in the body) is the main cause of death for patients with breast cancer, the leading female tumour in the industrialised countries and developing countries alike. The biology and treatment of breast cancer metastasis remains an active area of scientific and clinical investigation. Written by experts in the subject area, the book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies. This timely book provides the current knowledge in the area of breast cancer metastasis and will be of important reading material for oncologists, radiologists, cancer researchers, biologists and health worker. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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