Bibliothèque de L'IMIST/CNRST

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Binding and dissociation kinetics for different biosensor applications using fractals par Sadana, Ajit. Publication : [S.l.] Elsevier Science 2006 . 384 p. , The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces. * first book to provide detailed kinetic analysis of the binding and dissociation reactions that are occuring on the biosensor surface * addresses the area of analyte-receptor binding and dissociation kinetics occurring on biosensor surfaces * provides physical insights into reactions occuring on biosensor surfaces. 24 cm. Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Bone marrow and stem cell transplantation.   Publication : [S.l.] Humana Press 2007 . 234 p. , This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up. With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Metastasis of breast cancer / par Mansel,, R.E. Publication : [S.l.] : Springer, 2007 . 435 p. ; , Metastasis (spread of cancer in the body) is the main cause of death for patients with breast cancer, the leading female tumour in the industrialised countries and developing countries alike. The biology and treatment of breast cancer metastasis remains an active area of scientific and clinical investigation. Written by experts in the subject area, the book has covered a broad range of topics in the metastasis of breast cancer, from genetics, biology to clinical management. Main topics include genetic control, biology, growth factors, cell adhesion, cell motility and invasion, natures of bone metastasis, sentinel node therapies, hormonal links, new biomarkers and detection of micrometastasis, and diagnosis The book also covers the current treatment options including surgical management, chemotherapy and hormonal therapies. This timely book provides the current knowledge in the area of breast cancer metastasis and will be of important reading material for oncologists, radiologists, cancer researchers, biologists and health worker. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Optics / par CGIA,, Mike Freeman PhD MPhil BSc MInstP(Hon) Publication : [S.l.] : Butterworth-Heinemann, 2003 . 576 p. ; , Thoroughly updated and revised, this definitive textbook continues to be the best available resource on the theory of optics and applications in optometry, ophthalmology, and vision science. It presents a complete overview of basic topics in optics and provides a strong foundation for further learning. 24 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Peroxiredoxin systems : structures and functions / par Flohé,, Leopold. Publication : [S.l.] : Springer, 2007 . 410 p. ; , The peroxiredoxins represent an important emerging family of sulfhydryl-linked antioxidant proteins, apparently ubiquitously present in all known organisms. The antioxidant function of the peroxiredoxins complements that of other enzymic and non-enzymic systems within the cell. In addition, there is increasing evidence that the peroxiredoxins play a role in cell signalling, by controlling and/or sensing hydrogen peroxide and peroxynitrite levels. In this, the first book containing a broad survey on the peroxiredoxins, the editors succeeded to involve almost all groups that contributed significant insights into the emerging field. The diverse biological roles of the new protein family are discussed in the context of other antioxidant systems like those based on heme or selenium catalysis. Finally, related future perspectives, which range from antimicrobial therapy up to the understanding of human development and carcinogenesis, are highlighted. Specifically, the book will be of outstanding interest to researchers who want to understand how micro-organisms, plants and animals cope with oxidative stress and how such stress is recognized and linked to adaptive responses via redox regulation of cellular processes. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Radiation exposure and image quality in X-ray diagnostic radiology : physical principles and clinical applications / par Aichinger, Horst. Publication : [S.l.] : Springer, 2003 . 212 p. ; , The largest contribution to radiation exposure to the population as a whole arises from diagnostic X-rays. Protecting the patient from radiation is a major aim of modern health policy, and an understanding of the relationship between radiation dose and image quality is pivotal to optimising medical diagnostic radiology. In this volume the data provided for exploring these concerns are partly based on X-ray spectra, measured on diagnostic X-ray tube assemblies, and are supplemented by the results of measurements on phantoms and simulation calculations. X-ray mammography data makes up the main part of this book. The book also features an extremely useful CD-ROM containing a comprehensive database in the form of Excel-files. 29 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Toxic plants dangerous to humans and animals / par Bruneton, Jean. Publication : [S.l.] : Lavoisier, 2000 . 545 p. ; , Physicians, pharmacists and veterinarians who deal with accidental plant ingestions on a daily basis are largely ill-prepared to manage such cases. Reliable information is therefore scarce. "Toxic Plants" seeks to meet this need. Part 1 lists the common causes of plant induced incidents and accidents in humans. The risks are described, in particular those inherent to herbal drugs. Plant identification and medical treatment are discussed , as well as the specifics of animal poisoning, paying special attention to pets. Part 2 is a detailed discussion of the plant species, most frequently implicated. It includes the circumstances of the intoxication, symptoms, proposed treatment, toxic doses, and also elements of diagnosis, toxin identification and toxic mechanisms. This book contains more than 1300 literature references and the most recent statistics. Four dozen botanical families are classified alphabetically with over 350 plant species including 100 plant monographs and numerous illustrations. This highly educational tool gives a complete picture of the toxic potential of higher plants. 25 cm. Date : 2000 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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