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Biotransformations in organic chemistry : a textbook / par Faber, Kurt. Publication : [S.l.] : Springer, 2004 . 454 p. ; , The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts ? principles of stereoselective transformations, kinetics and enzyme properties ? the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C-C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques and the use of modified enzymes, are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. In this revised and corrected 5th edition, emphasis has been given to an improved didactic style in order to facilitate a deeper understanding of the underlying principles. New developments, such as dynamic resolution, stereo-inversion and enantio-convergent processes are included. 23 cm. Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Bone marrow and stem cell transplantation.   Publication : [S.l.] Humana Press 2007 . 234 p. , This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up. With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
Clinical textbook for veterinary technicians sixth edition / par ACVS,, Dennis M. McCurnin DVM MS Dipl. Publication : [S.l.] : Saunders, 2006 . 1280 p. ; , Now in full-color! Written by veterinarians, including many board-certified specialists, and veterinary technicians, this comprehensive textbook is divided into six major sections covering nearly all the major content areas in the veterinary technology curriculum. The text contains helpful learning features, including introductions, boxed technician tips, and suggested readings – all written at a level appropriate for technicians. * Comprehensive text covering all areas of the curriculum. * Written specifically for technicians. * Presents detailed information on the role of the technician in every aspect of veterinary practice. * Features helpful pedagogical aids such as introductions, suggested readings, and boxed Technician Tips. 29 cm. Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Clinical veterinary toxicology / par Plumlee, Konnie DVM Publication : [S.l.] : Mosby, 2003 . 504 p. ; , This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. * Most comprehensive toxicology book available * Written in a user-friendly style that makes it easy to master the content * Covers poisonings in both large and small domestic animals * The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information * The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs * The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment * The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information. 28 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Communicating toxicogenomics information to nonexperts : a workshop summary / par Nonexperts,, Committee on Communicating Toxicogenomics Information to. Publication : [S.l.] : National Academy Press, 2005 . 60 p. ; , BrochØ. 23 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Critical excitation methods in earthquake engineering / par Takewaki,, Izuru. Publication : [S.l.] : Elsevier Science, 2007 . 296 p. ; , Since the occurrence of earthquakes and their properties are very uncertain even with the present knowledge, it is too difficult to define reasonable design ground motions especially for important buildings. In the seismic resistant design of building structures, the concept of 'performance-based design' has become a new paradigm guaranteeing the maximum satisfaction of building owners. The quality and reliability of the performance-based design certainly depend on the scientific rationality of design ground motions. In order to overcome this problem, a new paradigm has to be posed. To the author's knowledge, the concept of 'critical excitation' and the structural design based upon this concept can become one of such new paradigms. This book introduces a new probabilistic and energy-based critical excitation approach to overcome several problems in the scientific and rational modelling of ground motions. The author hopes that this book will help the development of new seismic-resistant design methods of buildings for such unpredicted or unpredictable ground motions. - First comprehensive book for critical excitation methods - Including updated, cutting-edge research - Applicable to other worst-case analysis problems - Including comprehensive review of critical excitation methods - Including verification by comprehensive recorded ground motions. 25 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

Equine neonatal medicine : a case-based approach / par (LAIM),, Mary Rose Paradis DVM MS DACVIM. Publication : [S.l.] : Saunders, 2006 . 304 p. ; , This outstanding textbook and clinical reference takes a case-based approach to the basic pathophysiology, diagnosis, and treatment of disease in the newborn foal, along with neonatal pharmacology, nutrition, assessment, and high-risk pregnancies. * Features the latest advances in equine neonatology that have the potential to significantly increase the survival rate of critically ill foals. * Provides thorough coverage of both basic concepts and hot topics in the field, including pathophysiology, diagnosis, and treatment of disease in the newborn foal, along with information on nutrition, assessment, and high-risk pregnancies. * Case-based chapters use real-life scenarios to help the reader apply key concepts to actual practice. * Expert contributors are leaders in the field of equine neonatal medicine and ensure the accuracy and clinical relevance of all information. 29 cm. Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Equine respiratory diseases / par Rush, Bonnie. Publication : [S.l.] : Blackwell Science Ltd, 2004 . 344 p. ; , BrochØ. 25 cm. Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Experimental and surgical techniques in the rat, second edition / par Waynforth, H. B. Publication : [S.l.] : Academic Press, 1992 . 382 p. ; , The publication of this Second Edition, twelve years after the first, attests to the timelessness of the techniques used in experimental work with the rat. However, scientific progress inevitably brings to light new ideas and procedures. In particular, considerable progress has been made in the use of new anesthetics and analgesics. A completely new chapter has been written on these with unique emphasis on the applicability to the rat. The very variable standards of surgery that existed in the past are placed in perspective in another new chapter, which makes recommendations more in keeping with the higher standards now demanded of animal experimentation. A variety of new techniques have been added throughout to expand the usefulness of the book, and more illustrations have been added to help in the execution of the various procedures. One of the greatest advances in the last twelve years is a greater appreciation for the well-being of experimental animals, and references to a more humane and refined approach have been made throughout this edition. This greater awareness of welfare issues demands that experimental animals be handled and used correctly and compassionately, with as little suffering as possible, and has led to a marked improvement in the attitude to proper training. This book is still the only source which provides a detailed and up-to-date compilation of illustrated experimental methods for work with the rat. It will continue to be an invaluable reference to specific information for laboratory workers and will help considerably in training new investigators in the proper and considerate use of this species. Key Features * All surgical techniques have been revised and updated * A new section on anesthesia and post-operative care has been included * Presents new techniques, particularly cannulation. 24 cm. Date : 1992 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

GEOMETRY VI : RIEMANNIAN GEOMETRY / par Postnikov, M.M. Publication : [S.l.] : Springer, 2001 . 504 p. ; , Translated from the Russian Edition, the fifth book in the author's series "Lectures on Geometry," in which his various lectures are published. Provides an addendum to make the volume a self-contained work, and makes numerous changes to the Russian edition to make the material more digestible. 24 cm. Date : 2001 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

Geriatrics and gerontology of the dog and cat / par D. Hoskins , Johnny DVM Publication : [S.l.] : Saunders, 2003 . 432 p. ; , This groundbreaking reference is the first and only comprehensive book to address the needs of older dogs and cats, providing the veterinary clinician, veterinary student, and animal health technician with health-related information that is clinically relevant and quickly retrievable in a simple format. It offers a complete and practical review of the causes, incidence, clinical features, diagnosis, and management of both common and uncommon problems associated with the aging process and acquired illness. Each chapter offers tips on the physical examination of that body system and provides quick-reference tables for guidance on diagnosis and treatment. Because of the increased health problems in aging dogs and cats and the ardent attachment of the pet owner, veterinarians need to know more about aging so they may delay or minimize the progressive deterioration of aging and improve the quality of life for geriatric dogs and cats. 26 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

Handbook of evidence-based veterinary medicine / par Cockcroft, Peter. Publication : [S.l.] : Wiley-Blackwell, 2003 . 224 p. ; , Univ. of Cambridge, UK. Text explains the basis of evidence-based medicine and how it can be applied to veterinary practice. Discusses the process of diagnosis and use of clinical diagnostic decision support systems, how to search for the best available external evidence, and how to perform decision analysis. Expanded-outline format. Softcover. 25 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

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