Catalogue Bibliothèque de L'IMIST/CNRST › Résultats de la recherche pour 'ccl=su:Toxicology'

Clinical veterinary toxicology / par Plumlee, Konnie DVM Publication : [S.l.] : Mosby, 2003 . 504 p. ; , This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. * Most comprehensive toxicology book available * Written in a user-friendly style that makes it easy to master the content * Covers poisonings in both large and small domestic animals * The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information * The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs * The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment * The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information. 28 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

		Antibiotics the perfect storm par Shlaes, David M. Publication : [S.l.] Springer 2010 . 106 p. , Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Biopharmaceutics applications in drug development Publication : [S.l.] Springer 2007 . 402 p. , In the last two decades, the discipline of biopharmaceutics has undergone considerable advances, particularly with regard to bioavailability and bioequivalence as they relate to product quality and regulatory standards of approval. Textbooks in the field have not been able to keep up with the growth of current and emerging applications of regulatory aspects of biopharmaceutics. Biopharmaceutics Applications in Drug Development fills this gap. This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Clinical veterinary toxicology / par Plumlee, Konnie DVM Publication : [S.l.] : Mosby, 2003 . 504 p. ; , This book covers all aspects of toxicology, including toxic diseases of large animals, small animals, and exotic pets. It provides key information on how poisons affect the body, how the body responds to a foreign substance, how poisonings are diagnosed, and how poisonings are treated. Coverage includes every organ system of every species of animal with details on each body system's susceptibility to poison. Poisons affect animals differently depending on species, breed, age, gender, health status, and reproductive status. This resource addresses these differences, allowing the veterinarian to determine the class of toxicant, the mechanism of action, and the proper course of treatment. If confronted with an unknown poison, the information in this book will assist the veterinarian in formulating a list of potential poisons based on the clinical signs that the animal is exhibiting, and in choosing the appropriate tests to narrow the list to one or a few possible poisons. * Most comprehensive toxicology book available * Written in a user-friendly style that makes it easy to master the content * Covers poisonings in both large and small domestic animals * The Principles of Toxicology section provides comprehensive coverage of concepts & terminology, toxicokinetics, treatments, and regulatory information * The Manifestations of Toxicoses section is devoted to differentiating between poisons based on lesions and clinical signs * The Classes of Toxicants section offers detailed information on each poison, including sources, risk factors, pathophysiology, clinical signs and lesions, diagnostic testing, and treatment * The author is board-certified in toxicology, and the contributors are all toxicologists and educators, ensuring authoritative, up-to-date clinical information. 28 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1), Réserver Ajouter au panier (Supprimer)
		Pas d'image disponible Communicating toxicogenomics information to nonexperts : a workshop summary / par Nonexperts,, Committee on Communicating Toxicogenomics Information to. Publication : [S.l.] : National Academy Press, 2005 . 60 p. ; , BrochØ. 23 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Endotoxins : structure, function and recognition / Publication : [S.l.] Springer 2010 . 432 p. , Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases. The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Goodman & gilman's the pharmacological basis of therapeutics / par Brunton,, Laurence. Publication : [S.l.] : McGraw-Hill Professional, 2005 . 1984 p. ; , A Doody's Core Title ESSENTIAL PURCHASE! 5 STAR DOODY'S REVIEW! "The 11th edition of Goodman & Gilman continues to be the most comprehensive and authoritative single source on the pharmacology of drugs. The first edition was published by Alfred Gilman and Louis Goodman in 1941. It soon became known as the bible of pharmacology and, even though editorship and chapter authorships have changed continuously from edition to edition, this remains the gold standard of pharmacology textbooks....The print version should be on the reference shelf and the digital version on the computer desktop of all practicing pharmacologists, pharmacists, and physicians."-- Doody's Review Service (20060801) 26 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Progestins and the mammary gland : from basic science to clinical applications / Publication : [S.l.] : Springer, 2008 . 197 pages ; , Progestins play a key role in reproductive endocrinology and as pharmaceutical drugs for contraception and in combined hormone therapy. To further our understanding of progestin action in the mammary gland, an international symposium, attended by leading researchers from academia and industry, was held in Berlin, 21–23 March 2007. Genetic mouse models helped to elucidate the role of progestins, both in normal breast development and in disease. Mechanistic molecular studies inspired the design of new progestins with improved tissue selectivity. In addition, the clinical impact of progesterone receptor agonists and antagonists for the prevention and treatment of breast cancer was discussed. 22 cm. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (2), Réserver Ajouter au panier (Supprimer)
		Radiation exposure and image quality in X-ray diagnostic radiology : physical principles and clinical applications / par Aichinger, Horst. Publication : [S.l.] : Springer, 2003 . 212 p. ; , The largest contribution to radiation exposure to the population as a whole arises from diagnostic X-rays. Protecting the patient from radiation is a major aim of modern health policy, and an understanding of the relationship between radiation dose and image quality is pivotal to optimising medical diagnostic radiology. In this volume the data provided for exploring these concerns are partly based on X-ray spectra, measured on diagnostic X-ray tube assemblies, and are supplemented by the results of measurements on phantoms and simulation calculations. X-ray mammography data makes up the main part of this book. The book also features an extremely useful CD-ROM containing a comprehensive database in the form of Excel-files. 29 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Serotonin : molecular, functional and clinical aspects / Publication : Boston, MA : Birkhaeuser Verlag AG, Boston/Basel/Berlin, 2007 . 621 pages. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Systems biology in drug discovery and development : methods and protocols Publication : [S.l.] Humana Press 2010 . 352 p. , Due to the failing “one-drug-fits-all” model, it has become increasingly necessary to develop personalized medicine that treats whole systems and brings the right drug to the right patient with the right dosages. In Systems Biology in Drug Discovery and Development: Methods and Protocols, leading experts provide a practical, state-of-the-art, and holistic view of the translation of systems biology into better drug discovery and personalized medical practice. While the first part of the book describes cutting-edge technologies and methods in the field, the second part illustrates how the technologies can be applied in science for disease understanding and therapeutic discovery. As a volume in the highly successful Methods in Molecular Biology™ series, this collection provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Authoritative and up-to-date, Systems Biology in Drug Discovery and Development: Methods and Protocols covers topics from fundamental concepts to advanced technologies in order to best serve biomedical students and professionals at all levels who are interested in vital integrative studies in molecular biology, genetics, bioinformatics, bioengineering, biochemistry, physiology, pathology, microbiology, immunology, pharmacology, toxicology, drug discovery, and clinical medicine. 26 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Therapeutic uses of botulinum toxin. Publication : [S.l.] : Humana Press, 2007 . 242 p. ; , Therapeutic Uses of Botulinum Toxin outlines and examines our current understanding of botulinum toxin and its various therapeutic applications. The editors explore how this novel compound fits into a wide variety of treatment algorithms across medical subspecialties. Each chapter focuses on a particular symptom and explains how botulinum toxin is currently used for treatment. The chapter authors are all leaders in their fields and are respected for their progressive approach to treatment. Physicians will benefit not only from those chapters devoted to their particular sub-specialty, but from the inspiring success resulting from the use of botulinum toxin in other patient populations. The concluding chapter examines questions of immunity, explores economic issues, and attempts to forecast future directions for this novel and somewhat mysterious drug. Clinicians across a wide variety of disciplines will refer to this comprehensive reference time and time again. 26 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Transient receptor potential Publication : [S.l.] Springer 2007 . 632 p. , In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field have written 35 essays which describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs, from pharmacologists and physiologists to medical doctors, other scientists, students and lecturers. It fills a gap between pharmacology textbooks and latest manuscripts in scientific periodicals. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Veterinary toxicology basic and clinical principles Publication : [S.l.] Academic Press 2007 . 1224 p. , Veterinary Toxicology, 2nd edition is a unique single reference that teaches the basic principles of veterinary toxicology and builds upon these principles to offer an essential clinical resource for those practicing in the field. This reference book is thoroughly updated with new chapters and the latest coverage of topics that are essential to research veterinary toxicologists, students, professors, clinicians and environmentalists. Key areas include melamine and cyanuric acid, toxicogenomics, veterinary medical geology, toxic gases, toxicity and safety evaluation of new veterinary pharmaceuticals and much more. The 2nd edition of this popular book represents the collective wisdom of leading contributors worldwide and continues to fill an undeniable need in the literature relating to veterinary toxicology. New chapters covering important and timely topics such as melamine and cyanuric acid, toxicogenomics, toxic gases and veterinary medical geology Expanded look at international topics, such as epidemiology of animal poisonings, regulatory guidelines and poisonous plants in Europe Heavily contributed book with chapters written by qualified and well-experienced authorities across all areas of veterinary toxicology Problem solving strategies are offered for treatment as well as in-depth knowledge of the basic mechanisms of veterinary toxicology. 29 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1), Réserver Ajouter au panier (Supprimer)
		Veterinary toxicology / par Roder, Joseph D. Publication : Boston : Butterwoth-Heinemann, 2001 . x, 403 p. : 22 cm. Date : 2001 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1), Réserver Ajouter au panier (Supprimer)
		Biocombinatorial approaches for drug finding / Publication : Berlin ; \| New York : Springer, 2005 . 1 online resource (xviii, 284 pages) : Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Forensic science / Publication : . 1 online resource (xxxi, 742 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780444829986, Ajouter au panier (Supprimer)
		Potential industrial carcinogens and mutagens / par Fishbein, L. Publication : . 1 online resource (x, 534 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780444417770, Ajouter au panier (Supprimer)
		Veterinary toxicology / par Roder, Joseph D. Publication : . 1 online resource (x, 403 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780750672405, Ajouter au panier (Supprimer)
		Clinical veterinary toxicology / Publication : . 1 online resource (xxi, 477 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780323011259, Ajouter au panier (Supprimer)
		Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics Publication : . IX, 466 p. 110 illus., 12 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-0-387-75613-4, Ajouter au panier (Supprimer)

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