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Biogerontology : mechanisms and interventions   Publication : [S.l.] Wiley-Blackwell 2007 . 500 p. , Biological aging and interventionary strategies are investigated with the eventual goal of extending healthy human lifespan and minimizing the incidence of diseases associated with aging. Biogerontologists, evolutionary biologists, biodemographers, scientists in related basic research, clinicians, and dieticians came together in Istanbul, Turkey, to share their research and discuss the latest developments in this rapidly advancing field. This volume presents chapters representative of the highlights of the meeting, including contributions in the following areas: (1) biological and nonbiological factors affecting lifespan and the quality of life; (2) ethical and social issues related to lifespan and health-span extension; (3) novel areas of understanding aging -- physiological, cellular, and molecular aspects; (4) new technologies to understand and modulate aging; (5) the latest successful approaches in the prevention and treatment of age-related diseases; and (6) aging intervention, prevention, and modulation by genes, natural and synthetic molecules, and lifestyle modifications. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
Control and regulation of transport phenomena in the cardiac system   Publication : [S.l.] Wiley-Blackwell 2008 . 300 p. , Leading researchers in the life sciences and engineers involved in research of transport phenomena in biological systems have contributed chapters that identify, analyze, and modify the control and regulation mechanisms of transport phenomena in biological systems, with particular emphasis on the cardiac system. Included in the contributions to this volume are the following topics: signaling mechanisms and transport phenomena; blood-tissue exchange and inter-tissue transport; cellular membrane transport and endocytosis of ions and metabolites; intracellular transport, energetics, and molecular motors; system biology, uni- and multi-scale transport models, and hierarchical analysis; and clinical considerations -- cardiac protection, metabolic and pharmaceutical augmentation, and interferences. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 26 cm. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
Francisella tularensis biology, pathogenicity, epidemiology, and biodefense par Kwaik, Yousef Abu Publication : [S.l.] Wiley-Blackwell 2007 . 417 p. , This is the first book on tularemia. With the biodefense initiative, there has been a major boost by the NIH to fund studies on bioterrorism agents, including Francisella, which is classified as a A bioterrorism agent. With the major interest in biodefense and the major threats of bioterrorism, Francisella tularensis has become a major interest for microbiologists, cell biologists, immunologists, and infectious disease experts. The volume explores the mechanisms of pathogenesis, genetics and genetic manipulations, genomics and metagenomics, identification of vaccine candidates, animal models to study the disease process, mechanisms of protective immunity, pathophysiology, vaccine development, genetic susceptibility, more effective therapies, clinical diagnosis, and routine and rapid microbiological diagnostic tools. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Healthy aging and longevity : third international conference   Publication : [S.l.] Wiley-Blackwell 2007 . 500 p. , In a climate where many unsubstantiated claims are made, it is essential to have access to the best evidence-based knowledge on how to extend healthy life expectancy. Researchers, healthcare practitioners, and policy makers come together annually at the International Research Center for Healthy Ageing and Longevity to discuss, debate, and exchange ideas, and the proceedings of the most recent conference is contained in the chapters of this volume. Now, more than ever, a critical need exists for the development of appropriate policies so that aging is seen as a resource and not as an isolating and segregating experience. Solid research elucidating the processes of aging must be translated into strategies for clinical practice in order to respond to the needs of an aging population. The full spectrum of proven and potential aging interventions including pharmaceutical, nutritional, clinical, educational, policy, complementary, preventive, and restorative means were explored at this international meeting. The topics covered in this volume include the following: (1) Nutritional interventions in aging and age-associated disease, both diet and supplements; (2) dementia in an aging population; (3) the new caring -- financial and asset management and substitute decision-making by and for older people; (4) how we improve the quality of research into healthy aging; (5) promoting balance and preventing falls in an aging population; (6) population aging in developing countries; (7) promoting health and well-being of the older community; (8) hormone and metabolic interventions in aging; (9) community attitudes and approaches towards human life extension; (10) respecting the elders in our care; (11) the biology of healthy aging and longevity; (12) basic science and mechanisms of aging and longevity; (13) sustaining optimal aging -- inner strength and mutual support; (14) wellbeing, retirement planning and expectations of the baby-boomer generation; (15) natural and complementary approaches to age-associated disorders; (16) psychosocial predictors of healthy aging and longevity -- lessons from longitudinal studies; (17) healthy longevity -- lessons learned from the world's longest-lived people; (18) the aging brain; (19) baby-boomer work force participation; (20) quality of care and quality of life for the elderly; (21) frontiers of knowledge in biogerontology; (22) behavioural and social interventions for healthy aging and longevity. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
Reproductive biomechanics   Publication : [S.l.] Wiley-Blackwell 2007 . 352 p. , The reproductive system is composed of complex sub-systems, which are driven by sophisticated biochemical processes, whereas their performance is controlled by the same physical laws that exist in any mechanical process on Earth (e.g., Newton's laws). Accordingly, the understanding of any physiological phenomenon, including the development of a pathologic condition, requires comprehensive evaluation of the biophysical and biomechanical aspects of reproduction in concert with the biological and clinical features. Several of the scientists from around the world who investigate the physical aspects of the reproductive system have contributed to the eight sessions resulting in this volume. These reports encompass the following areas of inquiry: non-pregnant uterine peristalsis, placental vasculature and blood flow, myometrial contractility and calcium transport, mechanics of the uterus and cervix in pregnancy, mechanics of embryonic development, penile mechanics and hemodynamics, sperm propulsion, and pelvic floor mechanics. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),
Sodium-calcium exchange and the plasma membrane ca2+-atpase in cell function fifth international conference   Publication : [S.l.] Wiley-Blackwel 2007 . 400 p. , Ca2+ homeostasis and the plasma membrane Na+/Ca2+ exchanger are vital to many cellular functions and physiological processes. This volume, which is the proceedings of the fifth in a series of international conferences, includes contributions that merge molecular biology, biochemistry, biophysics, and physiology, providing novel insights that significantly advance our understanding of Na+/Ca2+ exchanger in areas ranging from molecular mechanisms to the involvement in human disease. Several important themes are addressed: (1) structure-function relationships of the exchanger; (2) regulation of the exchanger; (3) Na/Ca exchanger gene regulation; (4) cellular location and targeting of the exchanger; (5) NC(K)X and PMCA KO mice; (6) Na/Ca exchanger interactions with other proteins; (7) Na/Ca exchange in cardiac function; (8) Na/Ca exchange in neuronal function; (9) Ca2+-extruding mechanisms and apoptosis; (10) Na/Ca exchange in smooth muscle, kidney, and endocrine function; (11) Na/Ca exchange inhibitors: therapeutic opportunities. Experts in the field of the plasma membrane Ca2+-ATPase (PMCA) have also contributed. The rate of progress in this field has been rapidly increasing, and new concepts have emerged regarding the relation between molecular structure and physiological function. New ideas on physiological modes of regulation have been increasingly testable through the use of transgenic animal models. This volume and the conference that preceded it continue the tradition of sharing information to fuel new advances in this exciting and important area of research. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),
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