Bibliothèque de L'IMIST/CNRST

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Biotransformations in organic chemistry : a textbook / par Faber, Kurt. Publication : [S.l.] : Springer, 2004 . 454 p. ; , The use of biocatalysts, employed either as isolated enzymes or whole microbial cells, offers a remarkable arsenal of highly selective transformations for state-of-the-art synthetic organic chemistry. Over the last two decades, this methodology has become an indispensable tool for asymmetric synthesis, not only at the academic level, but also on an industrial scale. This well-established textbook on biocatalysis provides a basis for undergraduate and graduate courses in modern organic chemistry, as well as a condensed introduction into this field. After a basic introduction into the use of biocatalysts ? principles of stereoselective transformations, kinetics and enzyme properties ? the different types of reactions are explained according to the 'reaction principle', such as hydrolysis, reduction, oxidation, C-C bond formation, etc. Special techniques, such as the use of enzymes in organic solvents, immobilization techniques and the use of modified enzymes, are treated in a separate section. A final chapter deals with the basic rules for the safe and practical handling of biocatalysts. In this revised and corrected 5th edition, emphasis has been given to an improved didactic style in order to facilitate a deeper understanding of the underlying principles. New developments, such as dynamic resolution, stereo-inversion and enantio-convergent processes are included. 23 cm. Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

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Enzyme biocatalysis principles and applications   Publication : [Dordrecht] Springer. 2008 . x, 391 pages , "The book is intended to provide a sound basis for enzyme reactor design based on kinetic principles, and give an updated vision of the potentials and limitations of enzyme biocatalysis, especially with respect to recent applications in processes of organic synthesis. The book is structured in the form of a textbook that goes from basic principles of enzyme structure and function to reactor design for homogeneous systems with soluble enzymes, and heterogeneous systems with insolubilized enzymes. It contains an introductory chapter that gives an updated overview of enzyme technology, a chapter on enzyme production focused on large-scale operations, two chapters devoted to homogeneous and heterogeneous enzyme kinetics and a chapter on enzyme reactor design and operation based on enzyme kinetics principles, mass transfer limitations and enzyme inactivation. The book is complemented with case studies of biocatalytic processes of industrial relevance or potential, written by experts in those fields. Applications of proteases, acylases, lipases, aldolases and dehydrogenases in reactions of organic synthesis, and peroxidases in the degradation of recalcitrant organic compounds, are used as selected examples to illustrate the realities and potentials of enzymes as process catalysts." "Written for: Researchers and students in biochemistry, biotechnology, genetic engineering; an excellent book for those working in the field of enzyme technology."--MONO JACKET. 25 cm. Date : 2008 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1),

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