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Cardiovascular physiology / par Berne, MD,Robert M. Publication : [S.l.] : Mosby, 2001 . 312 p. ; , Part of Mosby's successful monograph series, Cardiovascular Physiology presents fundamental concepts clearly and concisely. Students gain a solid understanding on how the cardiovascular system functions in both health and disease. Throughout, excellent illustrations and consistent pedagogical features focus student learning. In addition, the clinical commentaries help students apply what they've learned to real-life clinical situations. 24 cm. Date : 2001 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

Textbook of respiratory cell and molecular biology / par Wardlaw,, A. J. Publication : [S.l.] : Informa Healthcare, 2002 . 500 p. ; , The dramatic advances made in molecular science and genetics during the last two decades have started to transform our understanding of the scientific basis of human disease. We are now at the threshold of understanding, at the level of an individual protein or gene, what has gone wrong and how we might put it right. This is as true in respiratory disease as in other specialities. The genetic basis for cystic fibrosis is now clear and gene replacement therapy is a real possibility; analysis of the fine structure of *a1-antitrypsin has revealed how mutations cause disease; and the secrets of how respiratory syncytial virus causes bronchiolitis in children are being unlocked. However, as the literature expands at an exponential rate, clinicians who may have last studied immunology or genetics at medical school, or scientists new to respiratory research, can find it increasingly difficuly to keep up-to-date. This book is aimed primarily at those with a special interest in respiratory disease, either as physicians or scientists, who want a detailed but clear explanation of our current understanding of the pathogenesis of common respiratory disease. While the book makes no apologies for exploring in detail the scientific complexities that underpin respiratory disease, it will have failed if it is not also an enjoyable and stimulating read. Although much remains to be known, this book provides both a reference and a benchmark against which future progress can be measured. 25 cm. Date : 2002 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

The Geometry of biological time / par Winfree, Arthur T. Publication : [S.l.] : Springer, 2001 . 808 p. ; , From cell division to heartbeat, clocklike rhythms pervade the activities of every living organism. The cycles of life are ultimately biochemical in mechanism but many of the principles that dominate their orchestration are essentially mathematical. The Geometry of Biological Time describes periodic processes in living systems and their non-living analogues in the abstract terms of nonlinear dynamics. Enphasis is given in phase singularities, waves, and mutual synchronization in tissues composed of many clocklike units. Also provided are descriptions of the best-studied experimental systems such as chemical oscillators, pacemaker neurons, circadian clocks, and excitable media organized into biochemical and bioelectrical wave patterns in two and three dimensions. No theoretical background is assumed; the required notions are introduced through an extensive collection of pictures and easily understood examples. This extensively updated new edition incorporates the fruits of two decades' further exploration guided by the same principles. Limit cycle theories of circadian clocks are now applied to human jet lag and are understood in terms of the molecular genetics of their recently discovered mechanisms. Supercomputers reveal the unforeseen architecture and dynamics of three-dimensional scroll waves in excitable media. Their role in life-threatening electrical aberrations of the heartbeat is exposed by laboratory experiments and corroborated in the clinic. These developments trace back to three basic mathematical ideas. 24 cm. Date : 2001 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

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