Catalogue Bibliothèque de L'IMIST/CNRST › Résultats de la recherche pour 'su:SCIENCE / Life Sciences / Cytology'

Textbook of respiratory cell and molecular biology / par Wardlaw,, A. J. Publication : [S.l.] : Informa Healthcare, 2002 . 500 p. ; , The dramatic advances made in molecular science and genetics during the last two decades have started to transform our understanding of the scientific basis of human disease. We are now at the threshold of understanding, at the level of an individual protein or gene, what has gone wrong and how we might put it right. This is as true in respiratory disease as in other specialities. The genetic basis for cystic fibrosis is now clear and gene replacement therapy is a real possibility; analysis of the fine structure of *a1-antitrypsin has revealed how mutations cause disease; and the secrets of how respiratory syncytial virus causes bronchiolitis in children are being unlocked. However, as the literature expands at an exponential rate, clinicians who may have last studied immunology or genetics at medical school, or scientists new to respiratory research, can find it increasingly difficuly to keep up-to-date. This book is aimed primarily at those with a special interest in respiratory disease, either as physicians or scientists, who want a detailed but clear explanation of our current understanding of the pathogenesis of common respiratory disease. While the book makes no apologies for exploring in detail the scientific complexities that underpin respiratory disease, it will have failed if it is not also an enjoyable and stimulating read. Although much remains to be known, this book provides both a reference and a benchmark against which future progress can be measured. 25 cm. Date : 2002 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

		Apoptosis and autoimmunity : from mechanisms to treatments. Publication : [S.l.] : Wiley-VCH, 2003 . 392 p. ; , This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases. It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies. 25 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Bone marrow and stem cell transplantation. Publication : [S.l.] Humana Press 2007 . 234 p. , This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up. With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Pas d'image disponible Cell signalling / par Hancock, John. Publication : [S.l.] : Oxford University Press, 2005 . 316 p. ; , BrochØ. 25 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		From dna photolesions to mutations, skin cancer and cell death. Publication : [S.l.] : Royal Society of Chemistry, 2006 . 340 p. ; , As modern day society takes an increasing interest in outdoor activities, its exposure to sunlight has never been greater. As a consequence, countries throughout the world are experiencing a dramatic increase in the incidences of skin carcinomas and melanomas. From DNA photolesions to mutations, skin cancer and cell death provides an authoritative source of information for photobiologists interested in the series of genetic events that occur in the skin, and eventually lead to cancer. With contributions from eminent scientists in the field, this book includes the latest information on DNA photolesions and repair, as well as the key mechanisms of solar UV in skin cancer initiation and development. Significant information relating to UV-induced photolesions and mechanisms of skin tumour occurrence is also included. By providing the basic phenomena underlying the science and an overview of the biological events that take place when cells are exposed to solar UV radiation, From DNA photolesions to mutations, skin cancer and cell death is suitable to all researchers interested in the process of photocarcinogenesis. 24 cm. Date : 2006 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Molecular biology and biotechnology a comprehensive desk reference. Publication : [S.l.] Wiley-VCH 1995 . 1072 p. , This is one volume 'library' of information on molecular biology, molecular medicine, and the theory and techniques for understanding, modifying, manipulating, expressing, and synthesizing biological molecules, conformations, and aggregates. The purpose is to assist the expanding number of scientists entering molecular biology research and biotechnology applications from diverse backgrounds, including biology and medicine, as well as physics, chemistry, mathematics, and engineering. 29 cm. Date : 1995 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Molecular evolution : a phylogenetic approach / par Page,, Roderick D.M. Publication : [S.l.] : Wiley-Blackwell, 1998 . 352 p. ; , The study of evolution at the molecular level has given the subject of evolutionary biology a new significance. Phylogenetic 'trees' of gene sequences are a powerful tool for recovering evolutionary relationships among species, and can be used to answer a broad range of evolutionary and ecological questions. They are also beginning to permeate the medical sciences. In this book, the authors approach the study of molecular evolution with the phylogenetic tree as a central metaphor. This will equip students and professionals with the ability to see both the evolutionary relevance of molecular data, and the significance evolutionary theory has for molecular studies. The book is accessible yet sufficiently detailed and explicit so that the student can learn the mechanics of the procedures discussed. The book is intended for senior undergraduate and graduate students taking courses in molecular evolution/phylogenetic reconstruction. It will also be a useful supplement for students taking wider courses in evolution, as well as a valuable resource for professionals. First student textbook of phylogenetic reconstruction which uses the tree as a central metaphor of evolution. Chapter summaries and annotated suggestions for further reading. Worked examples facilitate understanding of some of the more complex issues. Emphasis on clarity and accessibility. 25 cm. Date : 1998 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Peroxiredoxin systems : structures and functions / par Flohé,, Leopold. Publication : [S.l.] : Springer, 2007 . 410 p. ; , The peroxiredoxins represent an important emerging family of sulfhydryl-linked antioxidant proteins, apparently ubiquitously present in all known organisms. The antioxidant function of the peroxiredoxins complements that of other enzymic and non-enzymic systems within the cell. In addition, there is increasing evidence that the peroxiredoxins play a role in cell signalling, by controlling and/or sensing hydrogen peroxide and peroxynitrite levels. In this, the first book containing a broad survey on the peroxiredoxins, the editors succeeded to involve almost all groups that contributed significant insights into the emerging field. The diverse biological roles of the new protein family are discussed in the context of other antioxidant systems like those based on heme or selenium catalysis. Finally, related future perspectives, which range from antimicrobial therapy up to the understanding of human development and carcinogenesis, are highlighted. Specifically, the book will be of outstanding interest to researchers who want to understand how micro-organisms, plants and animals cope with oxidative stress and how such stress is recognized and linked to adaptive responses via redox regulation of cellular processes. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Serial analysis of gene expression. Publication : [S.l.] : Humana Press, 2007 . 208 p. ; , Serial Analysis of Gene Expression (SAGE): Digital Gene Expression Profiling facilitates the introduction of SAGE into the laboratory, and provides a framework for interpreting and comparing data derived from SAGE experiments. Of the several methods of genetic profiling available, only SAGE measures the expression of both known and unknown genes. SAGE studies encompass 50,000 tags and can provide detailed knowledge of the 2000 most highly expressed genes in the tissue sample. The SAGE protocols presented are detailed, fully annotated, and tested, and are all written by experienced SAGE researchers from around the world. Part 1 is dedicated to experimental procedures of SAGE and related methods including aRNA LongSAGE, SuperSAGE, DeepSAGE, and GMAT. Part 2 provides methods for extraction and filtration of tags, analysis of ditag populations, and completing statistically correct comparisons of gene expression profiles. Comparative transcriptomics enables scientists to understand the underlying genetics of biological changes such as development, disease, crop yield, and resistance. SAGE analysis is also used to obtain unknown tags, which can be used as gene-specific primers in Rapid Amplification of cDNA Ends (RACE) reactions to generate full-length transcripts for cloning and sequencing. This book will be an indispensable tool for any lab engaged in genetic profiling and comparative transcriptomics, and will help many laboratories to successfully implement tag-based sequencing methods and procedures and obtain comprehensive, useful, and interpretative data. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Textbook of respiratory cell and molecular biology / par Wardlaw,, A. J. Publication : [S.l.] : Informa Healthcare, 2002 . 500 p. ; , The dramatic advances made in molecular science and genetics during the last two decades have started to transform our understanding of the scientific basis of human disease. We are now at the threshold of understanding, at the level of an individual protein or gene, what has gone wrong and how we might put it right. This is as true in respiratory disease as in other specialities. The genetic basis for cystic fibrosis is now clear and gene replacement therapy is a real possibility; analysis of the fine structure of a1-antitrypsin has revealed how mutations cause disease; and the secrets of how respiratory syncytial virus causes bronchiolitis in children are being unlocked. However, as the literature expands at an exponential rate, clinicians who may have last studied immunology or genetics at medical school, or scientists new to respiratory research, can find it increasingly difficuly to keep up-to-date. This book is aimed primarily at those with a special interest in respiratory disease, either as physicians or scientists, who want a detailed but clear explanation of our current understanding of the pathogenesis of common respiratory disease. While the book makes no apologies for exploring in detail the scientific complexities that underpin respiratory disease, it will have failed if it is not also an enjoyable and stimulating read. Although much remains to be known, this book provides both a reference and a benchmark against which future progress can be measured. 25 cm. Date : 2002 Disponibilité : Exemplaires disponibles:* La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Pas d'image disponible The World of the cell / par Kleinsmith, Lewis J. Publication : [S.l.] : Benjamin-Cummings Publishing Company, Subs of Addison Wesley Longman, Inc, 2005 . 944 p. ; , Relié. 28 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1), Réserver Ajouter au panier (Supprimer)
		Human stem cell technology and biology : a research guide and laboratory manual / Publication : Hoboken, N.J. : Wiley-Blackwell, 2011 . xvii, 419 pages : 29 cm + Date : 2011 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		International review of cell and molecular biology. Volume 286 / Publication : . 1 online resource (viii, 306 pages) : Disponibilité : http://www.sciencedirect.com/science/book/9780123858597, Ajouter au panier (Supprimer)
		Cilia : model organisms and intraflagellar transport / Publication : . 1 online resource (xvi, 390 pages, [16] pages of plates) : Disponibilité : http://www.sciencedirect.com/science/book/9780123813770, Ajouter au panier (Supprimer)
		Liposomes. Part G / Publication : . 1 online resource (xlvii, 399 pages, [16] pages of plates) : Disponibilité : http://www.sciencedirect.com/science/book/9780123813794, Ajouter au panier (Supprimer)

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