IMIST


Epigenetics and Cancer. (notice n° 28183)

000 -LEADER
fixed length control field 07834cam a2200529Mi 4500
001 - CONTROL NUMBER
control field ocn682903998
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211202095106.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 101105s2010 enka ob 001 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency QCL
Language of cataloging eng
Transcribing agency QCL
Modifying agency CDX
-- OCLCQ
-- UPM
-- OCLCQ
-- OPELS
-- OCLCQ
-- UIU
-- OCLCF
Description conventions rda
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9780123808660 (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 0123808669 (electronic bk.)
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)682903998
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QH431.A1
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 616.9/94042
Edition number 22
049 ## - LOCAL HOLDINGS (OCLC)
Holding library TEFA
245 00 - TITLE STATEMENT
Title Epigenetics and Cancer.
Number of part/section of a work Part A /
Statement of responsibility, etc edited by Zdenko Herceg and Toshikazu Ushijima.
264 #1 -
-- London :
-- Academic Press,
-- 2010.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (xiv, 396 pages) :
Other physical details illustrations.
336 ## - CONTENT TYPE
Content Type Term text
Content Type Code txt
Source rdacontent
337 ## - MEDIA TYPE
Media Type Term computer
Media Type Code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier Type Term online resource
Carrier Type Code cr
Source rdacarrier
347 ## -
-- data file
-- rda
380 ## -
-- Bibliography
490 1# - SERIES STATEMENT
Series statement Advances in genetics ;
Volume number/sequential designation v. 70
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Machine generated contents note: 1. Introduction: Epigenetics and Cancer / Toshikazu Ushijima -- I. Introduction -- II. Basic Epigenetic Mechanisms -- Ghosts Above the Genes -- III. Epigenetic Events and Biological Phenomena -- Gene Wiring to Instruct Inheritance -- IV. Cancer Epigenome -- Zooming in on Genome-Wide Scale -- V. Epigenetics and Environmental Factors -- Where Your Genes Meet the Environment -- VI. Epigenetic Changes in Cancer -- Markers in Tracking Cancer Cells -- VII. Epigenetic Drugs on the Rise -- Waking Up Sleeping Beauty -- VIII. Epigenetics and Cancer Prevention -- Protect Your Epigenome -- IX. Epigenetics Databases and Computational Methodologies -- Resource and Toolbox for Community -- X. Closing Remarks -- References -- SECTION I BASIC EPIGENETIC MECHANISMS IN THE REGULATION OF CRITICAL CELLULAR PROCESSES -- 2. DNA Methylation and Cancer / Manel Esteller -- I. Introduction -- II. The Molecular Basis of DNA Methylation -- III. DNA Methylation Abnormalities in Cancer -- IV. DNA Methylation Markers -- V. Determining the Cancer DNA Methylome -- VI. Therapy Perspectives -- VII. Conclusions -- References -- 3. Histone Modifications and Cancer / Zdenko Herceg -- I. Introduction -- II. Chromatin Organization -- III. Histone Modifications -- IV. Role of Histone Modifications in Cellular Processes -- V. Deregulation of Histone Modifications as a Mechanism Underlying Cancer Development -- VI. Histone Modifications in Cancer as Potent Biomarkers -- VII. Conclusion and Future Directions -- References -- 4. Epigenetics and miRNAs in Human Cancer / George A. Calin -- I. Introduction -- II.miRNAs as Targets of Epigenetic Changes in Cancer -- III.epi-miRNAs: Regulators of the Epigenetic Machinery -- IV. Conclusion -- References -- 5. Interplay Between Different Epigenetic Modifications and Mechanisms / Rabih Murr -- I. Introduction -- II. Crosstalk Between Histone Modifications and Transcription -- III. Crosstalk Between Different Histone Modifications in Response to DNA Damage -- IV. Crosstalks Involving DNA Methylation and Transcription -- V. Conclusions and Perspectives -- References -- SECTION II EPIGENETIC EVENTS UNDERLYING BIOLOGICAL PHENOMENA -- 6. Genomic Imprinting Syndromes and Cancer / Eamonn Richard Maher -- I. Introduction -- II. The Importance of Biparental Contribution to the Mammalian Genome -- III. Mechanisms Involved in Genomic Imprinting -- IV. Mechanisms Leading to Disorders of Imprinting -- V. The 11p15.5 Imprinted Region -- VI. The 14q32 Imprinting Cluster -- VII.15q11-q13 Imprinted Region -- VIII. The 6q24 Imprinted Region -- IX. Global Genomic Imprinting Disorders: NLRP7 and Biparental Complete Hydatidiform Moles -- X. Summary/Conclusion -- References -- 7. Epigenetic Codes in Stem Cells and Cancer Stem Cells / Akira Watanabe -- I. Epigenetic Codes in Stem Cells -- II. Tissue-Specific Stem Cells and Cancer Stem Cells -- References -- 8. Inheritance of Epigenetic Aberrations (Constitutional Epimutations) in Cancer Susceptibility / Megan P. Hitchins -- I. Introduction -- II. Definitions -- III. Epimutation Conferring Floral Symmetry in Toadflax -- IV. Nomenclature and Origins of Epimutations in Humans -- V. Epimutation of the Mismatch Repair Genes in Cancer Susceptibility -- VI. Epimutations of Additional Cancer Genes in Cancer Susceptibility Syndromes -- VII. Constitutional Epimutations in Other Human Diseases -- VIII. Inheritance of Altered Epigenetic States in Mouse Phenotypes -- IX. Conclusions -- References -- SECTION III CANCER EPIGENOME -- 9. Cancer Epigenome / Stephan Beck -- I. Introduction -- II. Epigenome Analysis Approaches -- III. Cancer Epigenomes: Current State of Affairs -- IV. Potential Applications of Cancer Epigenomic Data for Risk Prediction, Diagnosis, Prognosis, and Therapy -- V. Head and Neck: Example of an Emerging Cancer Epigenome Project -- VI. Conclusion and Future Perspectives -- VII. Useful Links -- References -- 10. Identification of Driver and Passenger DNA Methylation in Cancer by Epigenomic Analysis / Gerd P. Pfeifer -- I. Introduction -- II. Aberrant DNA Methylation in Cancer -- Starting from Single Gene Studies -- III. Aberrant DNA Methylation in Cancer -- Genome-Wide Studies -- IV. Results from DNA Methylation Profiling -- V. Targeted Methylation of Genes Versus Methylation of Target Genes or "Passenger Methylation" Versus "Driver Methylation" -- VI. Inactivation of Important Biological Pathways by Cancer-Associated Methylation -- VII. Methylation of Noncoding RNA Promoters in Cancer -- VIII. Experiments that Could Distinguish Between "Driver Methylation" and "Passenger Methylation" in Cancer -- References -- 11. Epigenetic Drivers of Genetic Alterations / Hiromu Suzuki -- I. Introduction -- II. Genetic Instability and Cancer -- III. Epigenetic Drivers of Genetic Alterations -- IV. Concurrent Genetic and Epigenetic Alterations Associated With Cancer Cell Survival -- V. Conclusions -- References -- SECTION IV EPIGENETIC THERAPY AND EPIGENETIC DRUGS -- 12. DNA Demethylating Agents and Epigenetic Therapy of Cancer / Zdenko Herceg -- I. Introduction -- II. Epigenetic Deregulation in Cancer -- III. Epigenetic Therapies -- IV. Epigenetic Drugs -- V. Epigenetic Coupling Therapies -- VI. Concluding Remarks -- References -- 13. Histone Modification Therapy of Cancer / Saverio Minucci -- I. Introduction -- II. Histone Acetylation -- III. Histone Methylation -- IV. Perspectives -- References.
588 ## -
-- Description based on print version record.
520 ## - SUMMARY, ETC.
Summary, etc Genes interact with environment, experience, and the biology of the brain to shape an animal's behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity. * Explores latest topics in neural circuits and behavior research in zebrafish, drosophila, c.elegans, and mouse models * Includes methods for testing with ethical, legal, and social implications * Critically analyzes prospects future prospects.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer
General subdivision Genetic aspects.
9 (RLIN) 38536
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Epigenesis.
9 (RLIN) 957
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Carcinogenesis.
9 (RLIN) 38537
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer
General subdivision Genetic aspects.
Source of heading or term fast
-- (OCoLC)fst00845368
9 (RLIN) 38536
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Carcinogenesis.
Source of heading or term fast
-- (OCoLC)fst00846974
9 (RLIN) 38537
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Epigenesis.
Source of heading or term fast
-- (OCoLC)fst00914128
9 (RLIN) 957
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
9 (RLIN) 20
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Herceg, Zdenko.
9 (RLIN) 38538
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ushijima, Toshikazu.
9 (RLIN) 38539
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Advances in genetics ;
Volume number/sequential designation v. 70.
9 (RLIN) 2504
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://www.sciencedirect.com/science/book/9780123808660">http://www.sciencedirect.com/science/book/9780123808660</a>
938 ## -
-- Coutts Information Services
-- COUT
-- 16426433
-- 95.00 GBP
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Ebook
956 ## - LOCAL ELECTRONIC LOCATION AND ACCESS (OCLC)
Electronic name Consortium
994 ## -
-- C0
-- TEF

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