IMIST


Tumor Dormancy, Quiescence, and Senescence, Volume 1 (notice n° 46177)

000 -LEADER
fixed length control field 05630nam a22005055i 4500
001 - CONTROL NUMBER
control field 978-94-007-5958-9
003 - CONTROL NUMBER IDENTIFIER
control field DE-He213
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20211203074819.0
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
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008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130305s2013 ne | s |||| 0|eng d
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789400759589
-- 978-94-007-5958-9
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1007/978-94-007-5958-9
Source of number or code doi
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number RC261-271
072 #7 - SUBJECT CATEGORY CODE
Subject category code MJCL
Source bicssc
072 #7 - SUBJECT CATEGORY CODE
Subject category code MED062000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 614.5999
Edition number 23
245 10 - TITLE STATEMENT
Title Tumor Dormancy, Quiescence, and Senescence, Volume 1
Medium [electronic resource] :
Remainder of title Aging, Cancer, and Noncancer Pathologies /
Statement of responsibility, etc edited by M.A. Hayat.
264 #1 -
-- Dordrecht :
-- Springer Netherlands :
-- Imprint: Springer,
-- 2013.
300 ## - PHYSICAL DESCRIPTION
Extent XXIV, 324 p. 54 illus., 35 illus. in color.
Other physical details online resource.
336 ## - CONTENT TYPE
Content Type Term text
Content Type Code txt
Source rdacontent
337 ## - MEDIA TYPE
Media Type Term computer
Media Type Code c
Source rdamedia
338 ## - CARRIER TYPE
Carrier Type Term online resource
Carrier Type Code cr
Source rdacarrier
347 ## -
-- text file
-- PDF
-- rda
490 1# - SERIES STATEMENT
Series statement Tumor Dormancy and Cellular Quiescence and Senescence, Aging, Cancer, and Noncancer Pathologies ;
Volume number/sequential designation 1
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Preface.-I. Tumor dormancy -- Is tumor dormancy clinically relevant?- Microenvironmental influence on breast cancer Dormancy and metastasis -- Determination of breast cancer dormancy: analysis of Circulating free dna using snp 6.0 arrays -- Clonogenicity of cultured prostate cancer cells is controlled by dormancy : significance and comparison with cell culture models of breast cancer cell dormancy -- Dormancy and metastasis of melanoma cells to lymph Nodes, lung, and liver -- Late recurrence is a sign of melanoma dormancy: need of Life-long follow-up of elanoma patients. II. Quiescence -- Hematopoietic stem cell quiescence and long term Maintenance: role of scl/tal1 -- Regulation of muscle stem cell quiescent and Undifferentiated state: roles of hesr1 and hesr3 genes -- The kinase mirk/dyrk1b mediates a reversible quiescent State in a subset of ovarian, pancreatic, and colon cancers. III. Cellular senescence -- Stress -induced senescence: molecular pathways.-11 Accumulation of reactive oxygen species and induction Of premature senescence: role of ddb2 -- P21 mediates senescence by a mechanism involving accumulation of reactive oxygen species -- Role of micrornase and zeb1 downmodulation in oxidative  Stress-induced apoptosis and senescence.- Hypoxic response in senescent brain is impaired: possible  Contribution to neurodegeneration.-Enhancing reprogramming to pluripotency by controlling senescence -- Histone deacetylase inhibitor induces replicative Senescence of mesenchymal stem cells -- Senescence arrest of endopolyploid cells renders Senescence into one mechanism for positive tumorigenesis -- The two faces of senescence-associated epigenetic Alterations: tumor suppressors and oncogenic drivers.- Chemotherapy- and radiation-induced accelerated senescence: implications for treatment response, tumor progression, and cancer survivorship -- Suppression of cellular senescence in glioblastoma: role Of src homology domain-containing phosphatase 2 -- Chemotherapy of malignant pleural mesothelioma induces both senescence and apoptosis -- Microrna as a modulator of cell proliferation and Senescence: role in lung cancer cells -- Role of senescence induction in cancer therapy -- Cellular senescence limits the extent of fibrosis Following liver damage -- Formation of secretory senescent cells in prostate tumors: the role of androgen receptor activity and cell cycle regulation.-Index  .
520 ## - SUMMARY, ETC.
Summary, etc With a particular emphasis on tumor dormancy in breast, lung, prostate, and liver cancers, as well as in melanoma, this first volume of a new Springer series focuses on the interrelationship between biological processes of aging and tumors—both dormant and quiescent. With detail supplied by numerous international researchers at the forefront of cancer research, the book examines a host of differing aspects of the topic. Featured contributions analyze the role of the quiescent state in regulating hematopoietic and muscle stem cells. They also explore the mediation, by the kinase, in the reversible quiescent state of a subset of ovarian, pancreatic, and colon cancers. The book includes key research on the molecular mechanisms underlying stress-induced cellular senescence, in addition to those governing the accumulation of reactive oxygen species, and the induction of premature senescence. It also provides information on suppressing cellular senescence in the most common, and most aggressive malignant primary brain tumor in humans, glioblastoma multiforme. With comprehensive and cutting-edge information on therapeutic interventions and on the correct diagnosis of relevant neoplasms, and with numerous color illustrations, this is the most up-to-date assessment of current medical knowledge in this crucial area of medical research.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Medicine.
9 (RLIN) 184273
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer research.
9 (RLIN) 184274
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Public health.
9 (RLIN) 184275
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Stem cells.
9 (RLIN) 184276
650 14 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biomedicine.
9 (RLIN) 3969
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Cancer Research.
9 (RLIN) 184277
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Stem Cells.
9 (RLIN) 184278
650 24 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Public Health.
9 (RLIN) 184279
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hayat, M.A.
Relator term editor.
9 (RLIN) 16416
710 2# - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element SpringerLink (Online service)
9 (RLIN) 25138
773 0# - HOST ITEM ENTRY
Title Springer eBooks
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Printed edition:
International Standard Book Number 9789400759572
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE
Uniform title Tumor Dormancy and Cellular Quiescence and Senescence, Aging, Cancer, and Noncancer Pathologies ;
Volume number/sequential designation 1
9 (RLIN) 181088
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1007/978-94-007-5958-9">http://dx.doi.org/10.1007/978-94-007-5958-9</a>
912 ## -
-- ZDB-2-SBL
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Ebook
956 ## - LOCAL ELECTRONIC LOCATION AND ACCESS (OCLC)
Electronic name Springer

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