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Dna polymerases : (notice n° 5578)

000 -LEADER
fixed length control field 01943nam a2200277 u 4500
001 - CONTROL NUMBER
control field UNI0000324
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20161122163612.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130725s2010 XX eng
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9789814299169 (hardcover)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
International Standard Book Number 9814299162 (hardcover)
040 ## - CATALOGING SOURCE
Original cataloging agency DCLC
040 ## - CATALOGING SOURCE
Modifying agency IMIST
Description conventions AFNOR
041 1# - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 572.86
Edition number 22
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Hubscher, Ulrich.
245 #0 - TITLE STATEMENT
Title Dna polymerases :
Remainder of title discovery, characterization and functions in cellular dna transactions
Statement of responsibility, etc Ulrich Hubscher, Silvio Spadari, Giuseppe Villani, Giovanni Maga.
250 ## - EDITION STATEMENT
Edition statement 1st ed.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc [S.l.]
Name of publisher, distributor, etc World Scientific Publishing Company
Date of publication, distribution, etc 2010.
300 ## - PHYSICAL DESCRIPTION
Extent 340 p.
Dimensions 25 cm.
500 ## - GENERAL NOTE
General note Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Biochemistry
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element DNA polymerases
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Maga, Giovanni.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Spadari, Silvio.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Villani, Giuseppe.
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        La bibliothèque des Sciences Exactes et Naturelles La bibliothèque des Sciences Exactes et Naturelles   17804   572.86 HUB 0000000018766 11/22/2016 11/22/2016 Livre
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