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Molecular targeting and signal transduction

Collection : Cancer treatment and research . v. 119 Publié par : Kluwer Academic Publishers (Boston) Détails physiques : viii, 331 pages illustrations 24 cm. ISBN :1402078226; 9781402078224; 1402078471 (eBook); 9781402078477 (eBook). Année : 2004
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Livre La bibliothèque des Sciences Médicales et Pharmaceutiques
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Brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.

Includes bibliographical references and index.

Biology of the Epidermal Growth Factor Receptor Family -- Integrin Signaling in Cancer -- Regulators of Vascular Endothelial Growth Factor Expression in Cancer -- Integrin-Linked Kinase (ILK) in Combination Molecular Targeting -- p21-Activated Kinase 1: An Emerging Therapeutic Target -- Basis and Importance of Src as a Target in Cancer -- Therapeutic Targeting of the Receptor Tyrosine Kinase Met -- Nuclear Factor -- kB Activation Mediates Cellular Transformation, Proliferation, Invasion, Angiogenesis and Metastasis of Cancer -- The p53 Pathway: Targets for the Development of Novel Cancer Therapeutics -- Runx Protein Signaling in Human Cancers -- Signal Transduction Mediated by Cyclin D1: From Mitogens to Cell Proliferation: A Molecular Target with Therapeutic Potential -- Signal Transduction Pathways in Bcr-Abl Transformed Cells -- Estrogen Receptors and Anti-Estrogen Therapies -- Targeting Endothelin Axis in Cancer -- km23: A Novel TGFb Signaling Target Altered in Ovarian Cancer.

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