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Advances in genetics. Volume 82 /

Détails physiques : 1 online resource (120 pages) ISBN :9780124078024 (electronic bk.); 0124078028 (electronic bk.).
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Chapter One: The Repair and Signaling Responses to DNA Double-Strand Breaks -- Introduction -- Formation of DSBs -- Mechanisms of DSB Rejoining -- DNA Damage Response Signaling -- Functions of the DDR Assembly -- Regulation of DSB Repair Pathway Choice -- Contribution of Defects in DSB Rejoining Processes to Human Disease -- Concluding Remarks -- Chapter Two: Biological Activity and Biotechnological Aspects of Locked Nucleic Acids -- Brief Introduction -- Chemistry and Structure -- Biological Activity of LNA-Containing ONs -- LNA Pharmacology -- LNA in Biotechnology -- Concluding Remarks.

The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.

Includes index.

Description based on print version record.

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