Ciliary function in mammalian development /
Collection : Current topics in developmental biology, 0070-2153 ; . v. 85 Mention d'édition :First edition. Détails physiques : 1 online resource (xix, 464 pages, [32] pages of plates) : illustrations (some color). ISBN :9780080922478 (electronic bk.); 0080922473 (electronic bk.); 9780123744531 (electronic bk.); 0123744539 (electronic bk.).Includes bibliographical references and index.
Basal bodies: platforms for building cilia / Wallace F. Marshall -- Intraflagellar transport (IFT): role in ciliary assembly, resorption and signalling / Lotte B. Pedersen and Joel L. Rosenbaum -- How did the cilium evolve? / Peter Satir, David R. Mitchell, and Gáspár Jékely -- Ciliary tubulin and its post-translational modifications / Jacek Gaertig and Dorota Wloga -- Targeting protein to the ciliary membrane / Gregory J. Pazour and Robert A. Bloodgood -- Cilia: multifunctional organelles at the center of the vertebrate left-right asymmetry / Basudha Basu and Martina Brueckner -- Ciliary function and Wnt signal modulation / Jantje M. Gerdes and Nicholas Katsanis -- Primary cilia in planar cell polarity regulation of the inner ear / Chonnettia Jones and Ping Chen -- The primary cilium: at the crossroads of mammalian hedgehog signaling / Sunny Y. Wong and Jeremy F. Reiter -- The primary cilium coordinates signaling pathways in cell cycle control and migration during development and tissue repair / Søren T. Christensen ... [and others] -- Cilia involvement in patterning and maintenance of the skeleton / Courtney J. Haycraft and Rosa Serra -- Olfactory cilia: our direct neuronal connection to the external world / Dyke P. McEwen, Paul M. Jenkins, and Jeffrey R. Martens -- Ciliary dysfunction in developmental abnormalities and diseases / Neeraj Sharma, Nicolas F. Berberi, and Bradley K. Yoder.
Cilia - the tiny hair-like structures on the surface of cells - have been identified as playing a role in a variety of disease and developmental disorders. This volume presents the fresh findings in cilia research and thought on the role of cilia in disease and developmental abnormalities.


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