Free-radical-induced dna damage and its repair :
Mention d'édition :1st ed. Publié par : Springer, ([S.l.] :) Détails physiques : 544 p. ; 24 cm. ISBN :3540261206 (hardcover) ($399.00); 9783540261209 (hardcover). Année : 2006| Type de document | Site actuel | Cote | Statut | Date de retour prévue | Code à barres | Réservations |
|---|---|---|---|---|---|---|
| Livre | La bibliothèque des Sciences Exactes et Naturelles | 572.86 SON (Parcourir l'étagère) | Disponible | 0000000013184 |
Survol La bibliothèque des Sciences Exactes et Naturelles Étagères Fermer l'étagère
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| 572.86 SEI Analytics of protein-DNA interactions | 572.86 SEN VOL.1 Handbook of genome research | 572.86 SEN VOL.2 Handbook of genome research | 572.86 SON Free-radical-induced dna damage and its repair : | 572.86 STA Genomics : | 572.86028 DHA The comet assay in toxicology / | 572.861 177 COC Introduction to marine genomics |
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals have various sources, notably ionizing radiation and oxidative stress. In radiotherapy for cancer and with some anticancer drugs, use is made of cell death by excessive DNA damage. The mechanisms leading to products of free-radical attack which have been studied in models and with small double-stranded DNA fragments are discussed in detail, and the basics of the underlying free-radical chemistry are dealt with in separate chapters.


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