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Insulin and IGFs /

Autres auteurs : Litwack, Gerald.
Collection : Vitamins and hormones ; . v. 80 Mention d'édition :1st ed. Publié par : Academic Press, (Amsterdam ; | Boston :) Détails physiques : 1 online resource (xxii, 733 pages, [16] pages of plates) : illustrations (some color). ISBN :9780080922157; 0080922155; 9780123744081; 0123744083; 1282120891; 9781282120891. Année : 2009
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Includes bibliographical references and index.

The Human Insulin Superfamily of Polypeptide Hormones -- The Structure and Function of Insulin: Decoding the TR Transition -- Molecular Mechanisms of Differential Intracellular Signaling From the Insulin Receptor -- c-Abl and Insulin Receptor Signaling -- CXCL14 and Insulin Action -- Crosstalk Between Growth Hormone and Insulin Signaling -- Intracellular Retention and Insulin-Stimulated Mobilization of GLUT4 Glucose Transporters -- Compartmentalization and Regulation of Insulin Signaling to GLUT4 by the Cytoskeleton -- Nutrient Modulation of Insulin Secretion -- How Insulin Regulates Glucose Transport in Adipocytes -- Spatio-Temporal Dynamics of Phosphatidylinositol-3,4,5-Trisphosphate Signaling -- Serine Kinases of Insulin Receptor Substrate Proteins -- Phosphorylation of IRS Proteins: Yin-Yang Regulation of Insulin Signaling -- IRS-2 and Its Involvement in Diabetes and Aging -- Glucose-Dependent Insulinotropic Polypeptide (Gastric Inhibitory Polypeptide; GIP) -- Insulin Granule Biogenesis, Trafficking and Exocytosis -- Glucose, Regulator of Survival and Phenotype of Pancreatic Beta Cells -- Matrix Metalloproteinases, T Cell Homing and beta-Cell Mass in Type 1 Diabetes -- Role of Wnt Signaling in the Development of Type 2 Diabetes -- Retinal Insulin Receptor Signaling in Hyperosmotic Stress -- Interleukin-6 and Insulin Resistance -- Structure, Function, and Regulation of Insulin-Degrading Enzyme -- Modification of Androgen Receptor Function by Igf-1 Signaling: Implications in the Mechanism of Refractory Prostate Carcinoma -- Insulin-Like Growth Factor-2/Mannose-6 Phosphate Receptors -- Interactions of IGF-II with the IGF2R/Cation-Independent Mannose-6-Phosphate Receptor: Mechanism and Biological Outcomes.

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

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