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Molecular Testing in Cancer

Détails physiques : XI, 442 p. 87 illus., 84 illus. in color. online resource. ISBN :9781489980502.
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Exemplaires : http://dx.doi.org/10.1007/978-1-4899-8050-2

Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing --  Conventional and Molecular Cytogenetics in Cancer --  Comparative Genomic Hybridization and Array based CGH in Cancer --  Polymerase Chain Reaction -- Single Nucleotide Polymorphisms (SNPs) --  Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms -- Microarray-based Investigations in Cancer -- Proteomics in Cancer Diagnostics -- Circulating Tumor Cells: A Non-Invasive Liquid Biopsy in Cancer -- Molecular Testing in Hematological Malignancies -- Molecular Testing in Breast Cancer --  Molecular Pathology of Gastrointestinal Tumors -- Molecular Testing in Pulmonary Tumors -- Molecular testing in Gynecological Malignancies -- Molecular Testing in Central Nervous System tumors -- Molecular Testing in Adult Kidney Tumors --  Molecular Testing in Prostate Cancer -- Molecular Testing in Urothelial Tumors -- Molecular Testing in Thyroid Cancer -- Molecular Testing of Head and Neck Tumors --  Molecular Testing in Bone and Soft Tissue Tumors -- Molecular testing in Cutaneous Melanoma -- Molecular Testing in Pediatric Tumors -- Pharmacogenomics in Molecular Oncology -- Quality Assurance in Molecular Testing of Cancer.

Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers. Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.

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