Advances in virus research. Volume eighty seven /
Détails physiques : 1 online resource (259 pages) ISBN :9780124078475 (electronic bk.); 0124078478 (electronic bk.).Description based upon print version of record.
Front Cover; Advances in Virus Research; Copyright; Contents; Contributors; Chapter One: Mechanisms of Reovirus Bloodstream Dissemination; 1. Introduction; 1.1. Reoviruses; 1.2. Junctional adhesion molecule-A; 1.3. Reovirus pathogenesis; 1.4. Nonstructural protein 1s; 2. Dynamics of Reovirus Infection in the Intestine and Lung; 2.1. Infection via the gastrointestinal tract; 2.2. Infection via the respiratory tract; 3. Hematogenous Spread of Reovirus; 3.1. Transport of reovirus from the intestine to the bloodstream; 3.2. Reovirus viremia; 3.3. Role of receptors in reovirus dissemination
3.4. Function of nonstructural protein 1s in reovirus dissemination4. Neural Dissemination of Reovirus; 5. Function of Hematogenous and Neural Spread in Reovirus Pathogenesis; 6. Unanswered Questions and Future Directions; 6.1. How does reovirus enter and exit the bloodstream?; 6.2. How does 1s promote hematogenous spread?; 6.3. Clinical implications; Acknowledgments; References; Chapter Two: Molecular Biology and Epidemiology of Dianthoviruses; 1. Introduction; 2. Dianthoviruses; 2.1. CRSV; 2.2. RCNMV; 2.3. SCNMV; 2.4. FNSV; 2.5. Other suspected dianthoviruses
3. Economic Importance of Diseases Caused by Dianthoviruses4. Molecular Biology of Dianthovirus; 4.1. Genome organization; 4.2. Cap-independent translation; 4.3. Translation via -1 programmed ribosome frameshifting; 4.4. cis-Preferential requirement of replicase protein; 4.5. RNA elements required for genome replication; 4.6. Template recognition mechanisms of replicase proteins; 4.7. Composition of RNA replicase complexes; 4.8. Assembly of the replicase complex; 4.9. Viral RNA replication factory; 4.10. Subgenomic RNA; 4.11. A viral noncoding RNA; 4.12. Cell-to-cell and systemic movement
4.13. Virions4.14. Suppression of RNA silencing; 5. Transmission Studies and Epidemiology; 6. Effects on Environment; 6.1. Release of dianthoviruses from intact roots, decaying plant materials, and pollen grains; 6.2. Sewage; 7. Concluding Remarks and Perspectives; Acknowledgments; References; Chapter Three: Viral and Nonviral Elements in Potexvirus Replication and Movement and in Antiviral Responses*; 1. Introduction; 2. Elements That Regulate Potexvirus Replication; 2.1. Viral RNA elements; 2.2. Viral protein: RdRp; 2.3. Host cellular proteins involved in potexvirus replication
3. Elements That Regulate Potexvirus Movement3.1. CP: Virion structure and assembly; 3.2. TGB proteins: Virus cell-to-cell movement; 3.3. Host cellular proteins involved in potexvirus movement; 4. Elements Involved in Antiviral Responses; 4.1. Interactions between host and viral elements; 4.2. RNA-based antiviral defense; 5. Conclusions; Acknowledgments; References; Chapter Four: Influenza Virus Transcription and Replication; 1. Introduction; 2. Molecular Biology of Influenza Virus Transcription and Replication; 2.1. Organization of the viral genome
2.2. The viral transcription-replication cycle
Published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology.Contributions from leading authoritiesInforms and updates on all the latest developments in the field.
Includes bibliographical references.
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