Therapeutic applications of quadruplex nucleic acids /
Mention d'édition :1st ed. Publié par : Elsevier/AP, (Amsterdam :) Détails physiques : xii, 196 pages : illustrations ; 24 cm ISBN :9780123751386; 0123751381.
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Nucleic Acids
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therapeutic use.
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G-Quadruplexes.
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Molecular Targeted Therapy.
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Antineoplastic Agents
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therapeutic use.
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Antineoplastic Agents
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pharmacology.
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Neoplasms
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drug therapy.
| Type de document | Site actuel | Cote | Statut | Date de retour prévue | Code à barres | Réservations |
|---|---|---|---|---|---|---|
| Livre | La bibliothèque des Sciences Médicales et Pharmaceutiques | 615.36 NEI (Parcourir l'étagère) | Disponible | 0000000024583 |
Includes bibliographical references and index.
Introduction : quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I : anthraquinones and acridines -- Telomeric quadruplex ligands II : polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures.
"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--Page 4 of cover.
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