Bibliothèque de L'IMIST/CNRST

Free radical reactions have become increasingly important and a very attractive tool in organic synthesis in the last two decades, due to their powerful, selective, specific, and mild reaction abilities. Advanced Free Radical Reactions for Organic Synthesis reviews information on all types of practical radical reactions, e.g. cyclizations, additions, hydrogen-atom abstractions, decarboxylation reactions. The book usefully provides experimental details for the most important reactions as well as numerous references to the original literature. By covering both the fundamentals and synthetic applications it is therefore suitable for both new and experienced researchers, chemists, biochemists, natural product chemists and graduate students. This title is the definitive guide to radical chemistry for all scientists. - Introduces and reviews the use of radicals to perform synthetic transformations. - Practical details are provided for the most important methods. - Numerous references to the original literature.

What are free radicals. -- Functional group conversion. -- Intramolecular radical cyclizations. -- Intermolecular radical addition reactions. -- Alkylation of aromatics. -- Intramolecular hydrogen-atom abstraction. -- Synthetic uses of free radicals for nucleosides and sugars: Barton-McCombie reaction. -- Barton decarboxylation reaction with N-hydroxy-2-thiopyridone. -- Free radical reactions with metal hydrides. -- Stereochemistry in free radical reactions. -- Free radicals related to biology. -- Free radicals for green chemistry.

Includes bibliographical references and index.

Description based on print version record.