Catalogue Bibliothèque de L'IMIST/CNRST › Résultats de la recherche pour 'ccl=su:Toxicology'

Antibiotics the perfect storm par Shlaes, David M. Publication : [S.l.] Springer 2010 . 106 p. , Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

		Antibiotics the perfect storm par Shlaes, David M. Publication : [S.l.] Springer 2010 . 106 p. , Antibiotics are truly miracle drugs. As a class, they are one of the only ones that actually cure disease as opposed to most drugs that only help relieve symptoms or control disease. Since bacteria that cause serious disease in humans are becoming more and more resistant to the antibiotics we have today, and because they will ultimately become resistant to any antibiotic that we use for treatment or for anything else, we need a steady supply of new antibiotics active against any resistant bacteria that arise. However, the antibiotics marketplace is no longer attractive for large pharmaceutical companies, the costs of development are skyrocketing because of ever more stringent requirements by the regulatory agencies, and finding new antibiotics active against resistant strains is getting harder and harder. These forces are all combining to deny us these miracle drugs when we need them the most. I provide a number of possible paths to shelter from this perfect storm. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Endotoxins : structure, function and recognition / Publication : [S.l.] Springer 2010 . 432 p. , Endotoxins are potentially toxic compounds produced by Gram-negative bacteria including some pathogens. Unlike exotoxins, which are secreted in soluble form by live bacteria, endotoxins are comprised of structural components of bacteria. Endotoxins can cause a whole-body inflammatory state, sepsis, leading to low blood pressure, multiple organ dysfunction syndrome and death. This book brings together contributions from researchers in the forefront of these subjects. It is divided into two sections. The first deals with how endotoxins are synthesized and end up on the bacterial surface. The second discussed how endotoxins activate TLR4 and, in turn, how TLR4 generates the molecular signals leading to infectious and inflammatory diseases. The way endotoxins interact with the host cells is fundamental to understanding the mechanism of sepsis, and recent research on these aspects of endotoxins has served to illuminate previously undescribed functions of the innate immune system. This volume presents a description of endotoxins according to their genetic constitution, structure, function and mode of interaction with host cells. 24 cm. Date : 2010 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1), Réserver Ajouter au panier (Supprimer)
		Immunology in plant health and its impact on food safety / par Narayanasamy, P., Publication : New York : Food Products Press, 2005 . xviii, 412 pages : 23 cm Date : 2005 Disponibilité : http://catdir.loc.gov/catdir/toc/ecip0414/2004001749.html, http://www.e-streams.com/es0809/es0809_4284.html, http://www.e-streams.com/es0809/es0809_4324.html, Ajouter au panier (Supprimer)
		Immunology in plant health and its impact on food safety / par Narayanasamy, P., Publication : New York : Food Products Press, 2005 . xviii, 412 pages : 23 cm Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des sciences de l'ingénieur (1), Réserver Ajouter au panier (Supprimer)
		Immunotoxicology of drugs and chemicals. an experimental and clinical approach / Volume 1, Principles and methods of immunotoxicology : par Descotes, Jacques, Publication : . 1 online resource (1 volumes) : Disponibilité : http://www.sciencedirect.com/science/book/9780444510938, Ajouter au panier (Supprimer)
		Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics Publication : . IX, 466 p. 110 illus., 12 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-0-387-75613-4, Ajouter au panier (Supprimer)
		Encyclopedia of Medical Immunology Autoimmune Diseases / Publication : . 227 illus., 179 illus. in color. eReference. Disponibilité : http://dx.doi.org/10.1007/978-0-387-84828-0, Ajouter au panier (Supprimer)
		Trichloroethylene: Toxicity and Health Risks Publication : . X, 245 p. 23 illus., 13 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-1-4471-6311-4, Ajouter au panier (Supprimer)
		Diabetes and Viruses Publication : . XXIII, 373 p. Disponibilité : http://dx.doi.org/10.1007/978-1-4614-4051-2, Ajouter au panier (Supprimer)
		Immunomic Discovery of Adjuvants and Candidate Subunit Vaccines Publication : . X, 314 p. Disponibilité : http://dx.doi.org/10.1007/978-1-4614-5070-2, Ajouter au panier (Supprimer)
		Crossroads Between Innate and Adaptive Immunity IV Publication : . XII, 136 p. 15 illus., 3 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-1-4614-6217-0, Ajouter au panier (Supprimer)
		The Toxicant Induction of Irritant Asthma, Rhinitis, and Related Conditions Publication : . VI, 294 p. 24 illus., 18 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-1-4614-9044-9, Ajouter au panier (Supprimer)
		Encyclopedia of Medical Immunology Allergic Diseases / Publication : . 88 illus., 74 illus. in color. eReference. Disponibilité : http://dx.doi.org/10.1007/978-1-4614-9194-1, Ajouter au panier (Supprimer)
		Drugs Targeting B-Cells in Autoimmune Diseases Publication : . XI, 292 p. 3 illus., 2 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-3-0348-0706-7, Ajouter au panier (Supprimer)
		Cancer Immunotherapy Meets Oncology In Honor of Christoph Huber / Publication : . XX, 246 p. 19 illus., 18 illus. in color. Disponibilité : http://dx.doi.org/10.1007/978-3-319-05104-8, Ajouter au panier (Supprimer)
		Systems Biology of Free Radicals and Antioxidants Publication : . 489 illus., 273 illus. in color. eReference. Disponibilité : http://dx.doi.org/10.1007/978-3-642-30018-9, Ajouter au panier (Supprimer)
		Sphingolipids in Disease Publication : . VIII, 478 p. Disponibilité : http://dx.doi.org/10.1007/978-3-7091-1511-4, Ajouter au panier (Supprimer)
		Handbook of Glycosyltransferases and Related Genes Publication : . 205 illus., 75 illus. in color. eReference. Disponibilité : http://dx.doi.org/10.1007/978-4-431-54240-7, Ajouter au panier (Supprimer)

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