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Bone marrow and stem cell transplantation.   Publication : [S.l.] Humana Press 2007 . 234 p. , This volume is a compendium of cutting-edge molecular methods for the successful transplantation of hematopoietic stem cells. The availability of genetic profiles for committed and uncommitted stem cells combined with the determination of molecular steps involved in hematopoietic stem cell activation and self-renewal hold tremendous promise for future success in the clinic. Currently, stem cells can be quantified and sorted successfully, but transduction, labeling, and in vivo tracking of stem cells are difficult techniques with traditionally low efficiency levels. The contributors to this volume describe promising tools for stem cell transplant research models, such as in vivo bioluminescence imaging. Topics included in this volume are molecular profiling of hematopoietic stell cells, methods for imaging cell fates in hematopoiesis, PCR-SSP typing of HLA Class I and Class II alleles, sequence-based HLA typing, and typing minor HLA antigens. Also discussed in this volume are the roles of natural killer cells and killer inhibitor receptor polymorphisms, polymorphisms within epithelial receptors, molecular methods used for the detection of autologous graft contamination in lymphoid disorders, and the application of proteomics to posttransplantation follow-up. With the recent trend moving from gene expression to the protein expression profiles, the application of proteomics to the posttransplant follow-up of patients is becoming routine. As a result, this volume will become an invaluable source for biochemists, molecular biologists, and clinicians. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Communicating toxicogenomics information to nonexperts : a workshop summary / par Nonexperts,, Committee on Communicating Toxicogenomics Information to. Publication : [S.l.] : National Academy Press, 2005 . 60 p. ; , BrochØ. 23 cm. Date : 2005 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Elsevier's integrated review. Genetics / par Adkison, Linda R. Publication : Philadelphia, PA : Elsevier Saunders, 2012 . xi, 255 pages : , Revised edition of: Elsevier's integrated genetics / Linda R. Adkison, Michael D. Brown. c2007. | Includes index. 28 cm. Date : 2012 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Genetics in obstetrics and gynecology / par Simpson,, Joe Leigh, Publication : Philadelphia : Saunders, 2003 . xii, 484 p., 3 p. of plates : 27 cm. Date : 2003 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Human genes and genomes science, health, society par Rosenberg, Leon E. Publication : London | Oxford | Paris Academic Press 2012 . 1 vol. (xxiii, 421 p.) 29 cm Date : 2012 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

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Human genetics : from molecules to medicine / par Schaaf, Christian Patrick. Publication : Philadelphia : Wolters Kluwer/Lippincott Williams & Wilkins Health, 2012 . ix, 397 pages : 26 cm Date : 2012 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

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Nucleic acids hybridization : modern applications.   Publication : [S.l.] : Springer, 2007 . 316 p. ; , WatsonЀ“Crick hybridization of complementary sequences in nucleic acids is one of the most important processes necessary for molecular recognition in vivo, as well as nucleic acid identification and isolation. This book is devoted to a large family of in vitro DNA hybridization-based experimental techniques. A wide spectrum of experimental tasks covered by these approaches includes finding differential sequences in both genomic DNAs and mRNAs, genome walking, multiplex PCR, cDNA library construction starting from minute amount of total RNA, rapid amplification of cDNA 5Ѐ™ and 3Ѐ™ ends, effective smoothing of the concentrations of rare and abundant transcripts in cDNA libraries, recovery of promoter active repeats and differentially methylated genomic DNA, identification of common sequences in genomic or cDNA sources, new gene mapping, finding evolutionary conserved DNA and both single-nucleotide and extended mutation discovery or large-scale monitoring. Several approaches, such as microarray hybridization, have become extremely popular tools for specialists in biochemistry and in biomedicine, whereas the potential of many other advantageous techniques seems to be underestimated now. The international team of the authors of this book has tried both to elucidate the current state-of-art in hybridization techniques and to help the readers in choosing an appropriate method for performing an experiment in the most efficient way. Enclosed experimental protocols along with both comprehensive and detailed method descriptions make this truly universal book useful to all those interested in the modern life science methodologies. 24 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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Serial analysis of gene expression.   Publication : [S.l.] : Humana Press, 2007 . 208 p. ; , Serial Analysis of Gene Expression (SAGE): Digital Gene Expression Profiling facilitates the introduction of SAGE into the laboratory, and provides a framework for interpreting and comparing data derived from SAGE experiments. Of the several methods of genetic profiling available, only SAGE measures the expression of both known and unknown genes. SAGE studies encompass 50,000 tags and can provide detailed knowledge of the 2000 most highly expressed genes in the tissue sample. The SAGE protocols presented are detailed, fully annotated, and tested, and are all written by experienced SAGE researchers from around the world. Part 1 is dedicated to experimental procedures of SAGE and related methods including aRNA LongSAGE, SuperSAGE, DeepSAGE, and GMAT. Part 2 provides methods for extraction and filtration of tags, analysis of ditag populations, and completing statistically correct comparisons of gene expression profiles. Comparative transcriptomics enables scientists to understand the underlying genetics of biological changes such as development, disease, crop yield, and resistance. SAGE analysis is also used to obtain unknown tags, which can be used as gene-specific primers in Rapid Amplification of cDNA Ends (RACE) reactions to generate full-length transcripts for cloning and sequencing. This book will be an indispensable tool for any lab engaged in genetic profiling and comparative transcriptomics, and will help many laboratories to successfully implement tag-based sequencing methods and procedures and obtain comprehensive, useful, and interpretative data. 23 cm. Date : 2007 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Exactes et Naturelles (1),

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Genomics : applications in human biology / par Primrose, S. B. Publication : Malden, MA : Blackwell Pub., 2004 . xiv, 216 pages : Date : 2004 Disponibilité : Exemplaires disponibles: La bibliothèque des Sciences Médicales et Pharmaceutiques (1),

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